The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 129: Single-stranded DNA-binding protein 1, mitochondri...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
9 P09380 (/ISS) P09380 (/ISS) P09381 (/ISS) P09381 (/ISS) Q32PB0 (/ISS) Q5RDQ0 (/ISS) Q5RDQ0 (/ISS) Q95KK4 (/ISS) Q9CYR0 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
5 Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
5 Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q04837 (/IPI) Q04837 (/IPI) Q04837 (/IPI) Q04837 (/IPI) Q04837 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q9CYR0 (/ISO)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
1 P28042 (/NAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
5 Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS)
Positive regulation of helicase activity GO:0051096
Any process that activates or increases the activity of a helicase.
5 Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA)
Positive regulation of helicase activity GO:0051096
Any process that activates or increases the activity of a helicase.
1 Q9CYR0 (/ISO)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
1 Q9CYR0 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
15 A4D1U3 (/IDA) A4D1U3 (/IDA) A4D1U3 (/IDA) A4D1U3 (/IDA) A4D1U3 (/IDA) C9K0U8 (/IDA) C9K0U8 (/IDA) E7EUY5 (/IDA) E7EUY5 (/IDA) Q04837 (/IDA)
(5 more)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
9 P09380 (/ISS) P09380 (/ISS) P09381 (/ISS) P09381 (/ISS) Q32PB0 (/ISS) Q5RDQ0 (/ISS) Q5RDQ0 (/ISS) Q95KK4 (/ISS) Q9CYR0 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
5 Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS) Q04837 (/TAS)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
5 Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA) Q04837 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA) Q04837 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CYR0 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CYR0 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P28042 (/NAS)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
1 Q9CYR0 (/ISO)
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