The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 48: Protein Abitram

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
7 Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q9NX38 (/ISS) Q9NX38 (/ISS) Q9NX38 (/ISS)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
7 Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q9NX38 (/ISS) Q9NX38 (/ISS) Q9NX38 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9NX38 (/IPI) Q9NX38 (/IPI) Q9NX38 (/IPI)
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
1 Q80ZQ9 (/IDA)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
1 Q80ZQ9 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of actin filament polymerization GO:0030833
Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Regulation of actin filament polymerization GO:0030833
Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
1 Q80ZQ9 (/IMP)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
1 Q80ZQ9 (/IMP)
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 Q80ZQ9 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
12 Q1LU93 (/ISS) Q28G67 (/ISS) Q29S16 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5RFS0 (/ISS) Q5ZHW7 (/ISS) Q6GR35 (/ISS) Q6GR35 (/ISS) Q9NX38 (/ISS)
(2 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q581S9 (/IDA) Q581S9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q581S9 (/IDA) Q581S9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q80ZQ9 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q4Q2M3 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q2M3 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q80ZQ9 (/IDA)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
1 Q80ZQ9 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q80ZQ9 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
1 Q80ZQ9 (/IDA)
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
1 Q80ZQ9 (/IDA)
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