CATH Superfamily 2.40.30.130
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: alanine--tRNA ligase, cytoplasmic
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 19 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ser-tRNA(Ala) hydrolase activity GO:0002196
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
|
5 | P49588 (/ISS) P50475 (/ISS) Q5RC02 (/ISS) Q8CFX8 (/ISS) Q8CFX8 (/ISS) |
Aminoacyl-tRNA editing activity GO:0002161
The hydrolysis of an incorrectly aminoacylated tRNA.
|
4 | P50475 (/ISS) Q5RC02 (/ISS) Q8CFX8 (/ISS) Q8CFX8 (/ISS) |
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
|
3 | P49588 (/IDA) P50475 (/IDA) Q8BGQ7 (/IDA) |
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
|
3 | Q5RC02 (/ISS) Q8CFX8 (/ISS) Q8CFX8 (/ISS) |
Aminoacyl-tRNA editing activity GO:0002161
The hydrolysis of an incorrectly aminoacylated tRNA.
|
2 | P49588 (/IDA) Q8BGQ7 (/IDA) |
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P50475 (/IPI) |
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | Q8BGQ7 (/ISO) |
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P49588 (/TAS) |
Aminoacyl-tRNA editing activity GO:0002161
The hydrolysis of an incorrectly aminoacylated tRNA.
|
1 | Q8BGQ7 (/ISO) |
Ser-tRNA(Ala) hydrolase activity GO:0002196
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
|
1 | Q8BGQ7 (/IDA) |
Ser-tRNA(Ala) hydrolase activity GO:0002196
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
|
1 | Q8BGQ7 (/IMP) |
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
|
1 | Q8BGQ7 (/ISO) |
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
|
1 | P49588 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8BGQ7 (/IPI) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | P50475 (/IPI) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q8BGQ7 (/ISO) |
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
|
1 | P50475 (/IPI) |
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
|
1 | Q8BGQ7 (/ISO) |
Translation regulator activity GO:0045182
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
|
1 | Q8BGQ7 (/IMP) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
|
5 | P49588 (/ISS) P50475 (/ISS) Q5RC02 (/ISS) Q8CFX8 (/ISS) Q8CFX8 (/ISS) |
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
|
3 | P49588 (/IDA) P50475 (/IDA) Q8BGQ7 (/IDA) |
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
|
3 | Q5RC02 (/ISS) Q8CFX8 (/ISS) Q8CFX8 (/ISS) |
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
|
1 | Q8BGQ7 (/IDA) |
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
|
1 | Q8BGQ7 (/IMP) |
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
|
1 | P49588 (/TAS) |
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
|
1 | Q8BGQ7 (/IMP) |
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
|
1 | Q8BGQ7 (/ISO) |
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
|
1 | P49588 (/TAS) |
TRNA processing GO:0008033
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
|
1 | P49588 (/TAS) |
Cerebellar Purkinje cell layer development GO:0021680
The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
|
1 | Q8BGQ7 (/IMP) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | Q8BGQ7 (/IMP) |
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
|
1 | Q8BGQ7 (/IMP) |
Neuromuscular process GO:0050905
Any process pertaining to the functions of the nervous and muscular systems of an organism.
|
1 | Q8BGQ7 (/IMP) |
Regulation of cytoplasmic translational fidelity GO:0140018
Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.
|
1 | Q8BGQ7 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P50475 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8BGQ7 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P49588 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P49588 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8BGQ7 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P49588 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P49588 (/HDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P49588 (/HDA) |