The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Translation factors
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 88: Translation elongation factor EF-1, subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
13 Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS)
(3 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
13 Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS)
(3 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
13 Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS)
(3 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eukaryotic translation elongation factor 1 complex GO:0005853
A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
13 Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS) Q8IIC9 (/ISS)
(3 more)
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