The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Translation factors
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 34: Flavohemoprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nitric oxide dioxygenase activity GO:0008941
Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.
59 P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA)
(49 more)
Nitric oxide dioxygenase activity GO:0008941
Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.
54 P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP)
(44 more)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
53 P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA)
(43 more)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
53 P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA)
(43 more)
Hydroperoxide reductase activity GO:0032843
Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
53 P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA)
(43 more)
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
53 P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA) P24232 (/IDA)
(43 more)
6,7-dihydropteridine reductase activity GO:0004155
Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.
8 Q81T23 (/ISS) Q81T23 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS)
Riboflavin reductase (NADPH) activity GO:0042602
Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
5 Q2U124 (/IDA) Q2U124 (/IDA) Q2UDH4 (/IDA) Q2UDH4 (/IDA) Q2UDH4 (/IDA)
Nitric oxide dioxygenase activity GO:0008941
Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.
3 Q81T23 (/ISS) Q81T23 (/ISS) Q9URY5 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P39676 (/IPI) P39676 (/IPI)
Nitric oxide reductase activity GO:0016966
Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.
2 P39676 (/IMP) P39676 (/IMP)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
2 Q81T23 (/ISS) Q81T23 (/ISS)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
53 P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP) P24232 (/IEP)
(43 more)
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
53 P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP) P24232 (/IMP)
(43 more)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
6 Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS) Q9KMY3 (/ISS)
Cellular response to nitrosative stress GO:0071500
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
4 Q2U124 (/IMP) Q2U124 (/IMP) Q5AX11 (/IMP) Q5AX11 (/IMP)
Cellular response to nitrosative stress GO:0071500
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
3 Q54D73 (/IGI) Q9UAG7 (/IGI) Q9URY5 (/IGI)
Iron ion transport GO:0006826
The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q81T23 (/ISS) Q81T23 (/ISS)
Oxygen transport GO:0015671
The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q81T23 (/ISS) Q81T23 (/ISS)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P39676 (/IDA) P39676 (/IDA)
Sexual sporulation resulting in formation of a cellular spore GO:0043935
The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
2 Q5AX11 (/IMP) Q5AX11 (/IMP)
Negative regulation of sexual sporulation resulting in formation of a cellular spore GO:0043942
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
2 Q5AX11 (/IMP) Q5AX11 (/IMP)
Sterigmatocystin biosynthetic process GO:0045461
The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
2 Q5B7F8 (/IGI) Q5B7F8 (/IGI)
Sterigmatocystin biosynthetic process GO:0045461
The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
2 Q5AX11 (/IMP) Q5AX11 (/IMP)
Cellular response to misfolded protein GO:0071218
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
2 P39676 (/IMP) P39676 (/IMP)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 Q54D73 (/IMP) Q9UAG7 (/IMP)
Cellular response to reactive nitrogen species GO:1902170
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.
2 P39676 (/IMP) P39676 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q59MV9 (/IMP)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 Q59MV9 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q59MV9 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q59MV9 (/IMP)
Nitric oxide catabolic process GO:0046210
The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
1 Q59MV9 (/IMP)
Response to defense-related host nitric oxide production GO:0052565
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q59MV9 (/IMP)
Cellular detoxification of nitrogen compound GO:0070458
Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
1 Q9URY5 (/IGI)
Cellular response to nitrosative stress GO:0071500
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
1 Q59MV9 (/IEP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P39676 (/IDA) P39676 (/IDA) Q2U124 (/IDA) Q2U124 (/IDA) Q6FL28 (/IDA) Q6FL28 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P39676 (/HDA) P39676 (/HDA) Q9URY5 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q2UDH4 (/IDA) Q2UDH4 (/IDA) Q2UDH4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P39676 (/HDA) P39676 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P39676 (/HDA) P39676 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 P39676 (/IDA) P39676 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2 P39676 (/IDA) P39676 (/IDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
2 Q54D73 (/HDA) Q9UAG7 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9URY5 (/IC)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9URY5 (/HDA)
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