The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Catalase core domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Catalase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
21 P12365 (/IPI) P18122 (/IPI) P18123 (/IPI) P25819 (/IPI) Q0D9C4 (/IPI) Q0D9C4 (/IPI) Q0E4K1 (/IPI) Q0E4K1 (/IPI) Q0E4K1 (/IPI) Q0E4K1 (/IPI)
(11 more)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
19 P12365 (/IDA) P17598 (/IDA) P18122 (/IDA) P18123 (/IDA) P30567 (/IDA) Q0D9C4 (/IDA) Q0D9C4 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA)
(9 more)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
8 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) Q42547 (/ISS) Q96528 (/ISS) Q96528 (/ISS) Q96528 (/ISS)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
5 P25819 (/IDA) Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
2 P25819 (/IMP) Q8GB51 (/IMP)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q42547 (/IDA)

There are 42 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
16 P25819 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP)
(6 more)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
16 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP)
(6 more)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
16 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP)
(6 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
13 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP)
(3 more)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
13 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP)
(3 more)
Response to salt GO:1902074
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
13 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP)
(3 more)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
11 Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP)
(1 more)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
10 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP) Q10S82 (/IEP) Q42547 (/IEP) Q96528 (/IEP) Q96528 (/IEP) Q96528 (/IEP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
9 Q0D9C4 (/IEP) Q0D9C4 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP) Q0E4K1 (/IEP)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
5 P25819 (/IEP) Q42547 (/IEP) Q96528 (/IEP) Q96528 (/IEP) Q96528 (/IEP)
Cellular response to sulfate starvation GO:0009970
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
5 P25819 (/IEP) Q42547 (/IEP) Q96528 (/IEP) Q96528 (/IEP) Q96528 (/IEP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
5 P25819 (/IEP) Q42547 (/IEP) Q96528 (/IEP) Q96528 (/IEP) Q96528 (/IEP)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
5 P25819 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP)
Protein nitrosylation GO:0017014
The covalent addition of a nitric oxide group to an amino acid within a protein.
4 Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP)
Nitric oxide homeostasis GO:0033484
A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.
4 Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP)
Nitric oxide homeostasis GO:0033484
A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.
4 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
4 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS)
Hydrogen peroxide catabolic process GO:0042744
The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
4 Q42547 (/IGI) Q96528 (/IGI) Q96528 (/IGI) Q96528 (/IGI)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
4 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS)
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
4 Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP) Q10S82 (/IMP)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
3 P12365 (/IEP) P18122 (/IEP) P18123 (/IEP)
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
3 P12365 (/IEP) P18122 (/IEP) P18123 (/IEP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
3 P12365 (/IEP) P18122 (/IEP) P18123 (/IEP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
3 P12365 (/IDA) P18122 (/IDA) P18123 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P18122 (/IDA) P18123 (/IDA)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 P25819 (/IEP) Q42547 (/IEP)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
2 P18122 (/IMP) P18123 (/IMP)
Response to absence of light GO:0009646
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
2 Q0D9C4 (/IEP) Q0D9C4 (/IEP)
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
2 Q0D9C4 (/IEP) Q0D9C4 (/IEP)
Seed germination GO:0009845
The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
2 P17598 (/IDA) P30567 (/IDA)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
2 P12365 (/IDA) P18122 (/IDA)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
2 Q0D9C4 (/IDA) Q0D9C4 (/IDA)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 P18122 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P25819 (/IMP)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 P18123 (/TAS)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 P25819 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q8GB51 (/IMP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 P12365 (/TAS)
Photoperiodism GO:0009648
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
1 P25819 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 P18122 (/TAS)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 P18122 (/TAS)
Hydrogen peroxide catabolic process GO:0042744
The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
1 Q42547 (/TAS)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
14 Q0D9C4 (/IDA) Q0D9C4 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q10S82 (/IDA)
(4 more)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
11 P25819 (/IDA) Q0D9C4 (/IDA) Q0D9C4 (/IDA) Q10S82 (/IDA) Q10S82 (/IDA) Q10S82 (/IDA) Q10S82 (/IDA) Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA) Q0E4K1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 P18123 (/IDA) P25819 (/IDA) Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
6 P12365 (/TAS) P18122 (/TAS) Q42547 (/TAS) Q96528 (/TAS) Q96528 (/TAS) Q96528 (/TAS)
Cytosolic ribosome GO:0022626
A ribosome located in the cytosol.
5 P25819 (/IDA) Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
4 Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
4 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS) B8AME2 (/ISS)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
4 Q42547 (/IDA) Q96528 (/IDA) Q96528 (/IDA) Q96528 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P17598 (/IDA) P30567 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 P25819 (/IDA) Q42547 (/IDA)
Glyoxysome GO:0009514
A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.
2 P17598 (/TAS) P30567 (/TAS)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 Q42547 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
1 Q42547 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q42547 (/IDA)
Stromule GO:0010319
Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.
1 P25819 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q42547 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
1 Q42547 (/IDA)
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