The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cyclophilin-like
".
FunFam 15: Peptidyl-prolyl cis-trans isomerase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
|
1 | G5EEW6 (/IMP) |
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
|
1 | G5EEW6 (/IPI) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q6Q151 (/IDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9UUE4 (/NAS) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q9XYZ6 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q6Q151 (/IPI) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
1 | Q9XYZ6 (/IC) |
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
1 | G5EEW6 (/IMP) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | G5EEW6 (/IDA) |
Positive regulation of DNA-templated transcription, elongation GO:0032786
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
|
1 | G5EEW6 (/IMP) |
Positive regulation of RNA splicing GO:0033120
Any process that activates or increases the frequency, rate or extent of RNA splicing.
|
1 | G5EEW6 (/IMP) |
Positive regulation of vulval development GO:0040026
Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
1 | G5EEW6 (/IMP) |
Positive regulation of developmental growth GO:0048639
Any process that activates, maintains or increases the rate of developmental growth.
|
1 | G5EEW6 (/IMP) |
Positive regulation of mRNA processing GO:0050685
Any process that activates or increases the frequency, rate or extent of mRNA processing.
|
1 | G5EEW6 (/IMP) |
Positive regulation of oocyte development GO:0060282
Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | G5EEW6 (/IMP) |
Regulation of phosphorylation of RNA polymerase II C-terminal domain GO:1901407
Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
|
1 | Q9UUE4 (/IMP) |
Positive regulation of histone H3-K4 trimethylation GO:1905437
Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation.
|
1 | G5EEW6 (/IMP) |
Positive regulation of histone H3-K79 dimethylation GO:1905473
Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation.
|
1 | G5EEW6 (/IMP) |
Positive regulation of gastrulation GO:2000543
Any process that activates or increases the frequency, rate or extent of gastrulation.
|
1 | G5EEW6 (/IMP) |
Positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues GO:2001165
Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
|
1 | G5EEW6 (/IMP) |
Positive regulation of histone H3-K36 trimethylation GO:2001255
Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.
|
1 | G5EEW6 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | G5EEW6 (/IDA) Q6Q151 (/IDA) Q9UUE4 (/IDA) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q9UUE4 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9UUE4 (/HDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | G5EEW6 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q6Q151 (/IDA) |
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
|
1 | G5EEW6 (/IDA) |
Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
|
1 | Q9XYZ6 (/HDA) |
Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
|
1 | Q9XYZ6 (/HDA) |