The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Probable tRNA pseudouridine synthase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: H/ACA ribonucleoprotein complex non-core subunit N...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 P53919 (/IPI) P53919 (/IPI) Q96HR8 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 Q3UMQ8 (/ISS) Q52KK4 (/ISS) Q9VJ62 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P53919 (/IPI) P53919 (/IPI) Q96HR8 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q96HR8 (/HDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q96HR8 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q3UMQ8 (/ISO)
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
1 O14360 (/ISM)
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
1 Q96HR8 (/IPI)
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
1 Q3UMQ8 (/ISO)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
3 Q3UMQ8 (/ISS) Q52KK4 (/ISS) Q9VJ62 (/ISS)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
2 P53919 (/IMP) P53919 (/IMP)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
2 P53919 (/IPI) P53919 (/IPI)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
2 Q3UMQ8 (/TAS) Q96HR8 (/TAS)
SnoRNA guided rRNA pseudouridine synthesis GO:0000454
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
1 Q96HR8 (/ISS)
SnoRNA guided rRNA pseudouridine synthesis GO:0000454
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
1 Q3UMQ8 (/TAS)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
1 O14360 (/ISO)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
1 Q96HR8 (/ISS)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
1 O14360 (/IC)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
1 Q96HR8 (/TAS)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
1 Q96HR8 (/IDA)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
1 Q3UMQ8 (/ISO)
RNA stabilization GO:0043489
Prevention of degradation of RNA molecules.
1 Q3UMQ8 (/IMP)
RNA stabilization GO:0043489
Prevention of degradation of RNA molecules.
1 Q96HR8 (/ISS)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
1 Q96HR8 (/IMP)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
1 Q3UMQ8 (/ISO)
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
1 Q96HR8 (/IMP)
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
1 Q3UMQ8 (/ISO)
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
1 Q96HR8 (/IMP)
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
1 Q3UMQ8 (/ISO)
Positive regulation of telomerase RNA localization to Cajal body GO:1904874
Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
1 Q96HR8 (/HMP)
Telomerase holoenzyme complex assembly GO:1905323
The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.
1 Q96HR8 (/IMP)
Telomerase holoenzyme complex assembly GO:1905323
The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.
1 Q3UMQ8 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P53919 (/IDA) P53919 (/IDA) Q96HR8 (/IDA)
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
3 Q3UMQ8 (/ISS) Q52KK4 (/ISS) Q9VJ62 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O14360 (/HDA) Q19788 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P53919 (/IDA) P53919 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9LR70 (/IDA) Q9LR70 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q3UMQ8 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 O14360 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O14360 (/ISO)
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
1 Q96HR8 (/IDA)
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
1 Q3UMQ8 (/ISO)
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