The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Trypsin-like serine proteases
".
FunFam 6: Serine proteinase stubble
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
15 |
A1Z7M3 (/ISM)
A1Z7M4 (/ISM)
A8DY75 (/ISM)
B7YZU2 (/ISM)
E1JIW3 (/ISM)
Q05319 (/ISM)
Q05319 (/ISM)
Q8MS52 (/ISM)
Q9I7V4 (/ISM)
Q9VBY4 (/ISM)
(5 more) |
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
4 | P83748 (/IDA) Q8NF86 (/IDA) Q9JHJ7 (/IDA) Q9JHJ7 (/IDA) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
4 | E9Q409 (/IDA) Q80WM7 (/IDA) Q80X17 (/IDA) Q8R1A6 (/IDA) |
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
2 | Q80WM7 (/ISO) Q9QYZ9 (/ISO) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
2 | Q9JHJ7 (/ISO) Q9JHJ7 (/ISO) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
2 | Q80Z40 (/TAS) Q9Y6M0 (/TAS) |
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | Q9QYZ9 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9Y6M0 (/IPI) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | A1Z7M3 (/IMP) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | Q9QYZ9 (/ISA) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
1 | P83748 (/IDA) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
1 | Q9QYZ9 (/ISO) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
1 | Q9QYZ9 (/ISS) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
15 |
A1Z7M3 (/ISM)
A1Z7M4 (/ISM)
A8DY75 (/ISM)
B7YZU2 (/ISM)
E1JIW3 (/ISM)
Q05319 (/ISM)
Q05319 (/ISM)
Q8MS52 (/ISM)
Q9I7V4 (/ISM)
Q9VBY4 (/ISM)
(5 more) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
4 | E9Q409 (/IC) Q80WM7 (/IC) Q80X17 (/IC) Q8R1A6 (/IC) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
2 | P83748 (/IDA) Q8NF86 (/IDA) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
2 | Q80WM7 (/ISO) Q9QYZ9 (/ISO) |
|
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
|
2 | Q05319 (/IMP) Q05319 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q9JHJ7 (/TAS) Q9JHJ7 (/TAS) |
|
Liquid clearance, open tracheal system GO:0035002
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
|
2 | A1Z7M3 (/IMP) Q9W2C8 (/IMP) |
|
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
|
2 | Q05319 (/IMP) Q05319 (/IMP) |
|
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
2 | Q05319 (/IMP) Q05319 (/IMP) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
1 | Q9QYZ9 (/ISS) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P83748 (/IDA) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QYZ9 (/ISO) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QYZ9 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q80Z40 (/IEP) |
|
Lumen formation, open tracheal system GO:0035149
Creation of the central hole of a tube in an open tracheal system through which gases flow.
|
1 | B7YZU2 (/IEP) |
|
Trachea morphogenesis GO:0060439
The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
|
1 | B7YZU2 (/IMP) |
|
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
1 | Q8NF86 (/IDA) |
|
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
1 | Q80WM7 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
5 | E9Q409 (/IDA) Q80X17 (/IDA) Q8R1A6 (/IDA) Q9JHJ7 (/IDA) Q9JHJ7 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | E9Q409 (/IDA) Q80X17 (/IDA) Q8R1A6 (/IDA) Q920S2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q05319 (/ISS) Q05319 (/ISS) Q7RTY9 (/ISS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q7RTY9 (/TAS) Q9Y6M0 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | A1Z7M3 (/IDA) Q80WM7 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q402U7 (/IDA) Q8NF86 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q7RTY9 (/TAS) Q9Y6M0 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q80WM7 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Y6M0 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9Y6M0 (/TAS) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | A1Z7M3 (/IDA) |
|
Intracellular organelle GO:0043229
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
|
1 | Q920S2 (/IDA) |
|
Intracellular organelle GO:0043229
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
|
1 | Q7RTY9 (/ISS) |
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
1 | P83748 (/NAS) |
|
Perivitelline space GO:0098595
The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
|
1 | B7YZU2 (/HDA) |
