The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Trypsin-like serine proteases
".
FunFam 33: Replicase polyprotein 1a
There are 5 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Ubiquitinyl hydrolase 1.
[EC: 3.4.19.12]
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
|
520 |
A0A3G2KXK3
A0A3G2KXK3
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2 (510 more...) |
SARS coronavirus main proteinase.
[EC: 3.4.22.69]
TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
|
518 |
A0A3G2KXK3
A0A3G2KXK3
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2 (508 more...) |
RNA helicase.
[EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
|
246 |
A0A3G2KXK3
A0A3G2KXK3
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2 (236 more...) |
DNA helicase.
[EC: 3.6.4.12]
ATP + H(2)O = ADP + phosphate.
|
246 |
A0A3G2KXK3
A0A3G2KXK3
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2 (236 more...) |
RNA-directed RNA polymerase.
[EC: 2.7.7.48]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
|
246 |
A0A3G2KXK3
A0A3G2KXK3
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2
A7J8L2 (236 more...) |