The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Trypsin-like serine proteases
".
FunFam 22: Genome polyprotein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA-directed 5'-3' RNA polymerase activity GO:0003968
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
|
1 | P03300 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Induction by virus of host autophagy GO:0039520
Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
|
35 |
O41174 (/ISS)
O91734 (/ISS)
P03301 (/ISS)
P03302 (/ISS)
P03303 (/ISS)
P03313 (/ISS)
P06209 (/ISS)
P06210 (/ISS)
P07210 (/ISS)
P08291 (/ISS)
(25 more) |
|
Induction by virus of host autophagy GO:0039520
Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
|
2 | P03300 (/IDA) Q66282 (/IDA) |
|
Suppression by virus of host RIG-I activity GO:0039540
Any process in which a virus stops, prevents, or reduces the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
|
2 | P23008 (/IDA) Q82122 (/IDA) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | B2ZUN1 (/IDA) |
|
Suppression by virus of host translation initiation factor activity GO:0039611
Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.
|
1 | P03300 (/IDA) |
|
Suppression by virus of host translation initiation factor activity GO:0039611
Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.
|
1 | Q9YLJ1 (/ISS) |
|
Modulation by virus of host gene expression GO:0039656
The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
|
1 | P03313 (/IDA) |
|
Positive regulation by virus of host cytokine production GO:0044832
The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.
|
1 | P03313 (/IDA) |
|
Modulation by virus of host NIK/NF-kappaB signaling GO:0061765
Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.
|
1 | P03313 (/IC) |
|
Modulation by virus of host NIK/NF-kappaB signaling GO:0061765
Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.
|
1 | P03313 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P03313 (/IDA) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P03313 (/IMP) |