The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 21: Glutamate receptor interacting protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
5 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) Q925T6 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P97879 (/IPI) Q925T6 (/IPI) Q9WTW1 (/IPI) Q9Y3R0 (/IPI) |
|
Glutamate receptor binding GO:0035254
Interacting selectively and non-covalently with a glutamate receptor.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q9Y3R0 (/NAS) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P97879 (/IPI) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q925T6 (/ISO) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | Q9Y3R0 (/TAS) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9Y3R0 (/IPI) |
|
Receptor signaling complex adaptor activity GO:0030159
Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex.
|
1 | Q9Y3R0 (/NAS) |
|
Glucocorticoid receptor binding GO:0035259
Interacting selectively and non-covalently with a glucocorticoid receptor.
|
1 | Q9Y3R0 (/IPI) |
|
Glucocorticoid receptor binding GO:0035259
Interacting selectively and non-covalently with a glucocorticoid receptor.
|
1 | Q925T6 (/ISO) |
|
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | Q9Y3R0 (/NAS) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
5 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) Q925T6 (/ISO) |
|
Neurotransmitter receptor transport, endosome to postsynaptic membrane GO:0098887
The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
|
5 | E0CXE0 (/IDA) E0CXS4 (/IDA) E0CYS1 (/IDA) G3XA20 (/IDA) Q925T6 (/IDA) |
|
Neurotransmitter receptor transport, endosome to postsynaptic membrane GO:0098887
The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
|
5 | E0CXE0 (/IMP) E0CXS4 (/IMP) E0CYS1 (/IMP) G3XA20 (/IMP) Q925T6 (/IMP) |
|
Vesicle-mediated transport in synapse GO:0099003
Any vesicle-mediated transport that occurs in a synapse
|
5 | E0CXE0 (/IDA) E0CXS4 (/IDA) E0CYS1 (/IDA) G3XA20 (/IDA) Q925T6 (/IDA) |
|
Vesicle-mediated transport in synapse GO:0099003
Any vesicle-mediated transport that occurs in a synapse
|
5 | E0CXE0 (/IMP) E0CXS4 (/IMP) E0CYS1 (/IMP) G3XA20 (/IMP) Q925T6 (/IMP) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | E0CXE0 (/IDA) E0CXS4 (/IDA) E0CYS1 (/IDA) G3XA20 (/IDA) |
|
Positive regulation of neuron maturation GO:0014042
Any process that activates or increases the frequency, rate or extent of neuron maturation.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Artery smooth muscle contraction GO:0014824
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.
|
4 | E0CXE0 (/IMP) E0CXS4 (/IMP) E0CYS1 (/IMP) G3XA20 (/IMP) |
|
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
|
4 | E0CXE0 (/IMP) E0CXS4 (/IMP) E0CYS1 (/IMP) G3XA20 (/IMP) |
|
Positive regulation of AMPA glutamate receptor clustering GO:1904719
Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | P97879 (/IMP) Q9WTW1 (/IMP) |
|
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
|
1 | A8E0R9 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | P97879 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | Q925T6 (/ISO) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q925T6 (/IMP) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | F1NHU1 (/ISS) |
|
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
|
1 | A8E0R9 (/IMP) |
|
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
1 | Q9Y3R0 (/NAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
1 | Q9Y3R0 (/NAS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9Y3R0 (/NAS) |
|
Positive regulation of neuron projection arborization GO:0150012
Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
|
1 | P97879 (/IGI) |
|
Positive regulation of neuron projection arborization GO:0150012
Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
|
1 | Q925T6 (/ISO) |
|
Positive regulation of neuron projection arborization GO:0150012
Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
|
1 | Q9Y3R0 (/ISS) |
There are 31 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
6 | E0CXE0 (/IDA) E0CXS4 (/IDA) E0CYS1 (/IDA) G3XA20 (/IDA) P97879 (/IDA) Q925T6 (/IDA) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
5 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) Q925T6 (/ISO) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
5 | E0CXE0 (/IMP) E0CXS4 (/IMP) E0CYS1 (/IMP) G3XA20 (/IMP) Q925T6 (/IMP) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Neuron spine GO:0044309
A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
4 | E0CXE0 (/ISO) E0CXS4 (/ISO) E0CYS1 (/ISO) G3XA20 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9C0E4 (/TAS) Q9Y3R0 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9C0E4 (/TAS) Q9Y3R0 (/TAS) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
2 | P97879 (/IDA) Q9WTW1 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | A8E0R9 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q925T6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9Y3R0 (/ISS) |
|
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
1 | A8E0R9 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9WTW1 (/IDA) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q9WTW1 (/IDA) |
|
Mitochondrial cloud GO:0032019
A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
|
1 | A8E0R9 (/IDA) |
|
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q925T6 (/IDA) |
|
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q9Y3R0 (/ISS) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | P97879 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q925T6 (/ISO) |
|
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | Q925T6 (/IDA) |
|
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | F1NHU1 (/ISS) |
|
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q9WTW1 (/IDA) |
|
Pole plasm GO:0045495
Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
|
1 | A8E0R9 (/IDA) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
1 | P97879 (/IDA) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
1 | Q925T6 (/ISO) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q925T6 (/ISO) |
