The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Urease, subunit C, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Urease subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Urease activity GO:0009039
Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
13 A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA)
(3 more)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
10 A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA)
Urease activity GO:0009039
Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
2 C8VTF2 (/IMP) Q9SR52 (/IMP)
Urease activity GO:0009039
Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
1 O00084 (/EXP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
10 A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP) A0A0H3LAR3 (/IEP)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
2 E0ZS48 (/IDA) Q9SR52 (/IDA)
Urea catabolic process GO:0043419
The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
2 C8VTF2 (/IMP) O00084 (/IMP)
Urea catabolic process GO:0043419
The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
1 O00084 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Urease complex GO:0035550
A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).
10 A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA) A0A0H3LAR3 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O00084 (/HDA)
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