The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alpha-1-antitrypsin, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
541
3D
1uhgD01 - 94.1
2
416
3D
6hgnA02 - 96.8
3
291
3D
9apiA01 - 82.7
6
142
3D
3lw2A02 - 93.3
4
138 - - 91.8
11
115
3D
4eb1L02 - 77.8
5
102
3D
3fgqB01 - 61.7
8
91
3D
1xu8B02 - 79.5
7
88
3D
1imvA01 - 65.2
9
87
3D
4dy7F02 - 45.8
10
82
3D
2r9yA02 - 84.6
18
51
3D
2wy0C01 - 91.2
14
49
3D
4ga7B02 - 81.0
15
47
3D
2oayA02 - 89.7
12
47 - - 85.4
13
46 - - 83.3
16
45
3D
3le2A02 - 90.2
17
45
3D
3h5cA02 - 76.7
19
41
3D
4p0oA02 - 95.8
72
Heat shock protein 47 Collagen binding protein 1
31
3D
4au4G02 - 24.3
20
30 - - 34.3
61
26
3D
4rsqL01 - 53.1
21
26 - - 76.2
22
22 - - 83.2
50
18
3D
2h4rA02 - 75.3
23
17 - - 88.4
25
16 - - 94.4
24
16 - - 18.0
26
15 - - 80.3
27
13 - - 83.7
28
13 - - 90.3
29
12 - - 76.7
30
12 - - 96.5
34
12
3D
1f0cA02 - 18.4
33
11 - - 22.1
32
11 - - 79.7
36
11 - - 76.1
31
11 - - 82.8
35
serpin
11 - - 89.7
37
10 - - 71.3
71
10
3D
4zk3A02 - 53.4
39
9 - - 2.6
40
9 - - 91.7
44
9
3D
1k9oI02 - 92.2
38
9 - - 50.2
41
8 - - 29.0
43
8 - - 97.6
53
8
3D
3ndaB02 - 84.3
42
8 - - 95.9
48
serpin
7 - - 18.7
46
7 - - 85.5
65
7
3D
3dy0A02 - 23.7
49
7 - - 10.3
45
7 - - 46.9
47
7 - - 84.5
60
6 - - 71.7
62
6 - - 77.6
56
6 - - 15.7
58
6 - - 21.6
51
6 - - 22.7
55
6 - - 12.2
57
6 - - 83.8
52
alpha-2 antiplasmin, pigment epithelium-derived factor
6 - - 50.9
59
6 - - 74.3
54
antithrombin
6 - - 9.6
69
serpin
5 - - 18.3
67
5 - - 8.9
68
5 - - 53.0
63
5 - - 0.8
70
5 - - 10.3
64
5 - - 13.1
66
5 - - 13.5
78
4 - - 5.4
80
4 - - 4.3
82
4 - - 0.0
76
SERPIN
4 - - 69.1
74
4 - - 54.0
81
4 - - 16.5
77
4 - - 8.3
79
4 - - 13.9
83
4 - - 70.7
75
4 - - 68.0
73
4 - - 23.2
89
3 - - 0.0
90
C1 inhibitor
3 - - 1.8
84
serpin
3 - - 13.5
85
3 - - 3.1
87
3 - - 5.6
91
3 - - 4.4
86
3 - - 9.3
88
3 - - 73.1
92
2 - - 11.7
105
2 - - 4.2
99
Alpha-1 antiproteinase, antitrypsin
2 - - 5.5
103
2 - - 7.2
96
2 - - 12.4
94
2 - - 0.0
98
Serpin-2
2 - - 0.0
102
2 - - 32.3
100
2 - - 41.5
93
2 - - 39.2
101
2 - - 37.5
95
2 - - 0.0
106
2 - - 3.0
104
2 - - 0.0
97
2 - - 9.2
112
1 - - 0.0
129
1 - - 0.0
124
1 - - 0.0
131
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
141
1 - - 0.0
119
1 - - 0.0
110
1 - - 0.0
163
1 - - 0.0
126
1 - - 0.0
143
1 - - 0.0
133
1 - - 0.0
137
1 - - 0.0
154
1 - - 0.0
147
1 - - 0.0
117
1 - - 0.0
135
1 - - 0.0
145
1 - - 0.0
152
ovalbumin
1 - - 0.0
109
1 - - 0.0
121
1 - - 0.0
160
1 - - 0.0
107
1 - - 0.0
130
1 - - 0.0
140
1 - - 0.0
115
1 - - 0.0
150
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
123
1 - - 0.0
142
1 - - 0.0
128
1 - - 0.0
158
1 - - 0.0
132
1 - - 0.0
149
1 - - 0.0
111
1 - - 0.0
139
1 - - 0.0
113
1 - - 0.0
144
1 - - 0.0
125
1 - - 0.0
156
1 - - 0.0
118
1 - - 0.0
134
1 - - 0.0
127
1 - - 0.0
153
1 - - 0.0
136
1 - - 0.0
116
1 - - 0.0
108
1 - - 0.0
155
1 - - 0.0
120
1 - - 0.0
161
1 - - 0.0
146
1 - - 0.0
164
1 - - 0.0
151
1 - - 0.0
138
1 - - 0.0
122
1 - - 0.0
114
1 - - 0.0
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