The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Actin; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Actin, alpha skeletal muscle

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
Mesenchyme migration GO:0090131
The process in which the population of cells that make up a mesenchyme undergo directed movement.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
Endocardial cushion morphogenesis GO:0003203
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
1 A0A2R8RQJ8 (/IMP)
Endocardial cushion formation GO:0003272
The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
1 A0A2R8RQJ8 (/IMP)
Atrioventricular canal development GO:0036302
The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.
1 A0A2R8RQJ8 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
13 G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS) G3RUH8 (/ISS)
(3 more)
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