The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Mechanosensitive ion channel family protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mechanosensitive ion channel activity GO:0008381
Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress.
66 P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP) P0AAT4 (/IMP)
(56 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
66 P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI) P0AAT4 (/IPI)
(56 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
66 P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI) P0AAT4 (/IGI)
(56 more)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
66 P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP) P0AAT4 (/IEP)
(56 more)
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q47UQ4 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
66 P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA) P0AAT4 (/IDA)
(56 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
66 P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA) P0AAT4 (/RCA)
(56 more)
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