The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Myosin S1 fragment, N-terminal
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Myosin heavy chain 95F

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microfilament motor activity GO:0000146
Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
2 Q01989 (/NAS) Q01989 (/NAS)
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
2 Q01989 (/NAS) Q01989 (/NAS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q01989 (/IDA) Q01989 (/IDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q01989 (/IMP) Q01989 (/IMP)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q01989 (/NAS) Q01989 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q01989 (/IPI) Q01989 (/IPI)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
2 Q01989 (/IPI) Q01989 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2 Q01989 (/IDA) Q01989 (/IDA)
Myosin light chain binding GO:0032027
Interacting selectively and non-covalently with a light chain of a myosin complex.
2 Q01989 (/IPI) Q01989 (/IPI)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
2 Q01989 (/NAS) Q01989 (/NAS)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2 Q01989 (/IDA) Q01989 (/IDA)
Myosin VI light chain binding GO:0070856
Interacting selectively and non-covalently with a light chain of a myosin VI complex.
2 Q01989 (/IPI) Q01989 (/IPI)

There are 41 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus organization GO:0006997
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
2 Q01989 (/IMP) Q01989 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2 Q01989 (/IMP) Q01989 (/IMP)
Spindle organization GO:0007051
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
2 Q01989 (/IMP) Q01989 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q01989 (/IMP) Q01989 (/IMP)
Sperm individualization GO:0007291
The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.
2 Q01989 (/IGI) Q01989 (/IGI)
Sperm individualization GO:0007291
The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.
2 Q01989 (/IMP) Q01989 (/IMP)
Ovarian follicle cell migration GO:0007297
The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.
2 Q01989 (/IMP) Q01989 (/IMP)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
2 Q01989 (/IMP) Q01989 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
2 Q01989 (/IEP) Q01989 (/IEP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
2 Q01989 (/IMP) Q01989 (/IMP)
Metamorphosis GO:0007552
A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
2 Q01989 (/IMP) Q01989 (/IMP)
Imaginal disc morphogenesis GO:0007560
The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
2 Q01989 (/IMP) Q01989 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
2 Q01989 (/IMP) Q01989 (/IMP)
Larval chitin-based cuticle development GO:0008363
Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
2 Q01989 (/IMP) Q01989 (/IMP)
Morphogenesis of follicular epithelium GO:0016333
The process in which the anatomical structures of a follicular epithelium are generated and organized.
2 Q01989 (/IMP) Q01989 (/IMP)
Cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte GO:0019749
The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.
2 Q01989 (/IDA) Q01989 (/IDA)
Cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte GO:0019749
The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.
2 Q01989 (/IMP) Q01989 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 Q01989 (/IMP) Q01989 (/IMP)
Actin filament-based movement GO:0030048
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
2 Q01989 (/IDA) Q01989 (/IDA)
Actin filament-based movement GO:0030048
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
2 Q01989 (/NAS) Q01989 (/NAS)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
2 Q01989 (/IMP) Q01989 (/IMP)
Pseudocleavage involved in syncytial blastoderm formation GO:0030589
Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
2 Q01989 (/IMP) Q01989 (/IMP)
Pseudocleavage involved in syncytial blastoderm formation GO:0030589
Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
2 Q01989 (/TAS) Q01989 (/TAS)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
2 Q01989 (/IMP) Q01989 (/IMP)
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 Q01989 (/IMP) Q01989 (/IMP)
Regulation of actin filament-based process GO:0032970
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
2 Q01989 (/IGI) Q01989 (/IGI)
Regulation of actin filament-based process GO:0032970
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
2 Q01989 (/IMP) Q01989 (/IMP)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
2 Q01989 (/IMP) Q01989 (/IMP)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
2 Q01989 (/IMP) Q01989 (/IMP)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
2 Q01989 (/TAS) Q01989 (/TAS)
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
2 Q01989 (/IGI) Q01989 (/IGI)
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
2 Q01989 (/IMP) Q01989 (/IMP)
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
2 Q01989 (/TAS) Q01989 (/TAS)
Cell-cell junction maintenance GO:0045217
The maintenance of junctions between cells.
2 Q01989 (/TAS) Q01989 (/TAS)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
2 Q01989 (/IMP) Q01989 (/IMP)
Mitochondrion transport along microtubule GO:0047497
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
2 Q01989 (/IDA) Q01989 (/IDA)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q01989 (/NAS) Q01989 (/NAS)
Nucleus localization GO:0051647
Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
2 Q01989 (/IMP) Q01989 (/IMP)
Neuroblast division GO:0055057
The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.
2 Q01989 (/IMP) Q01989 (/IMP)
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
2 Q01989 (/TAS) Q01989 (/TAS)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
2 Q01989 (/TAS) Q01989 (/TAS)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q01989 (/IDA) Q01989 (/IDA)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
2 Q01989 (/IDA) Q01989 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
2 Q01989 (/IDA) Q01989 (/IDA)
Unconventional myosin complex GO:0016461
A portmanteau term for myosins other than myosin II.
2 Q01989 (/IDA) Q01989 (/IDA)
Unconventional myosin complex GO:0016461
A portmanteau term for myosins other than myosin II.
2 Q01989 (/NAS) Q01989 (/NAS)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
2 Q01989 (/IDA) Q01989 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
2 Q01989 (/IDA) Q01989 (/IDA)
Myosin VI complex GO:0031476
A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
2 Q01989 (/IPI) Q01989 (/IPI)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q01989 (/IPI) Q01989 (/IPI)
Germline ring canal GO:0045172
Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
2 Q01989 (/IDA) Q01989 (/IDA)
Basal part of cell GO:0045178
The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
2 Q01989 (/IDA) Q01989 (/IDA)
Sperm individualization complex GO:0070864
A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.
2 Q01989 (/IDA) Q01989 (/IDA)
Investment cone GO:0070865
A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.
2 Q01989 (/IDA) Q01989 (/IDA)
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