The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"CAP Gly-rich-like domain
".
FunFam 14: Uncharacterized protein, isoform E
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
6 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) O01349 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
6 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) O01349 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O42667 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q6A029 (/ISO) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q6A029 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of synapse structure or activity GO:0050803
Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
6 | A0A0B4KFR5 (/IMP) A0A0B4KG24 (/IMP) A0A0B4LGK5 (/IMP) A1ZA18 (/IMP) A4UZI0 (/IMP) O01349 (/IMP) |
|
Establishment of spindle orientation GO:0051294
Any process that set the alignment of spindle relative to other cellular structures.
|
6 | A0A0B4KFR5 (/IMP) A0A0B4KG24 (/IMP) A0A0B4LGK5 (/IMP) A1ZA18 (/IMP) A4UZI0 (/IMP) O01349 (/IMP) |
|
Nuclear migration involved in conjugation with cellular fusion GO:0000743
The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.
|
1 | O42667 (/IMP) |
|
Meiosis I GO:0007127
The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
|
1 | O42667 (/IGI) |
|
Dynein-driven meiotic oscillatory nuclear movement GO:0030989
Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.
|
1 | O42667 (/IMP) |
|
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
|
1 | Q6A029 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
6 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) O01349 (/IDA) |
|
Microtubule plus-end GO:0035371
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
|
6 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) O01349 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q6A029 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q6A029 (/ISO) |
|
Dynactin complex GO:0005869
A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.
|
1 | O42667 (/TAS) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
1 | O42667 (/IDA) |
|
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | Q6A029 (/ISO) |
|
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | O42667 (/HDA) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q6A029 (/ISO) |
|
Paranode region of axon GO:0033270
An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
|
1 | Q6A029 (/ISO) |
|
Meiotic spindle pole body GO:0035974
The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | O42667 (/IDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | O42667 (/IDA) |
|
Cell cortex of cell tip GO:0051285
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
|
1 | O42667 (/IDA) |
|
Nucleus leading edge GO:0110092
The area of a motile nucleus closest to the direction of movement.
|
1 | O42667 (/IDA) |
|
Cortical microtubule plus-end GO:1903754
The plus-end of a cortical microtubule.
|
1 | O42667 (/IDA) |