CATH Superfamily 2.30.30.140
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 179: E3 ubiquitin-protein ligase UHRF1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Hemi-methylated DNA-binding GO:0044729
Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Maintenance of DNA methylation GO:0010216
Any process involved in maintaining the methylation state of a nucleotide sequence.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Histone ubiquitination GO:0016574
The modification of histones by addition of ubiquitin groups.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Euchromatin GO:0000791
A dispersed and relatively uncompacted form of chromatin.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Heterochromatin GO:0000792
A compact and highly condensed form of chromatin.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
|
Replication fork GO:0005657
The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
|
2 | B6CHA3 (/ISS) F6UA42 (/ISS) |
