CATH Superfamily 2.30.30.140

FunFam 13: Histone acetyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 25 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	74	E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) E2RE71 (/IPI) (64 more)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	41	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (31 more)
Peptide-lysine-N-acetyltransferase activity GO:0061733 Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.	41	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (31 more)
Peptide-lysine-N-acetyltransferase activity GO:0061733 Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.	33	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (23 more)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone acetyltransferase activity GO:0004402 Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone acetyltransferase activity GO:0004402 Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	23	Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) (13 more)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Phospholipase binding GO:0043274 Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.	23	Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) (13 more)
Phospholipase binding GO:0043274 Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Protein-containing complex binding GO:0044877 Interacting selectively and non-covalently with a macromolecular complex.	23	Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) Q99MK2 (/IPI) (13 more)
Protein-containing complex binding GO:0044877 Interacting selectively and non-covalently with a macromolecular complex.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Peptide-lysine-N-acetyltransferase activity GO:0061733 Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Repressing transcription factor binding GO:0070491 Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone acetyltransferase activity GO:0004402 Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	20	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (10 more)
Histone acetyltransferase activity GO:0004402 Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	20	Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) (10 more)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
Acetyltransferase activity GO:0016407 Catalysis of the transfer of an acetyl group to an acceptor molecule.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	18	Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) (8 more)
Repressing transcription factor binding GO:0070491 Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.	18	Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) Q92993 (/IPI) (8 more)
Euchromatin binding GO:1990188 Interacting selectively and non-covalently with euchromatin, a dispersed and relatively uncompacted form of chromatin.	2	Q960X4 (/IDA) Q960X4 (/IDA)

There are 57 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Positive regulation of autophagy GO:0010508 Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	41	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (31 more)
Peptidyl-lysine acetylation GO:0018394 The acetylation of peptidyl-lysine.	41	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (31 more)
Positive regulation of autophagy GO:0010508 Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	33	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (23 more)
Peptidyl-lysine acetylation GO:0018394 The acetylation of peptidyl-lysine.	33	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (23 more)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Double-strand break repair GO:0006302 The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	23	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (13 more)
Apoptotic process GO:0006915 A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	23	Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) (13 more)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Response to heat GO:0009408 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	23	Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) (13 more)
Response to ionizing radiation GO:0010212 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Positive regulation of autophagy GO:0010508 Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone acetylation GO:0016573 The modification of a histone by the addition of an acetyl group.	23	Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) Q99MK2 (/IMP) (13 more)
Histone acetylation GO:0016573 The modification of a histone by the addition of an acetyl group.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Peptidyl-lysine acetylation GO:0018394 The acetylation of peptidyl-lysine.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Negative regulation of interleukin-2 production GO:0032703 Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone H4 acetylation GO:0043967 The modification of histone H4 by the addition of an acetyl group.	23	Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) Q99MK2 (/NAS) (13 more)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	23	Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) Q8CHK4 (/IGI) (13 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Cellular response to hydrogen peroxide GO:0070301 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	23	Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) (13 more)
Cellular response to estradiol stimulus GO:0071392 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Cellular response to X-ray GO:0071481 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).	23	Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) Q99MK2 (/IEP) (13 more)
Positive regulation of protein acetylation GO:1901985 Any process that activates or increases the frequency, rate or extent of protein acetylation.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Histone acetylation GO:0016573 The modification of a histone by the addition of an acetyl group.	20	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (10 more)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	18	Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) (8 more)
DNA double-strand break processing GO:0000729 The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
DNA replication GO:0006260 The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
Double-strand break repair GO:0006302 The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	18	Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) (8 more)
Double-strand break repair via nonhomologous end joining GO:0006303 The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Response to ionizing radiation GO:0010212 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Androgen receptor signaling pathway GO:0030521 Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	18	Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) (8 more)
Negative regulation of interleukin-2 production GO:0032703 Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	18	Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) (8 more)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	18	Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) Q92993 (/NAS) (8 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	18	Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) Q92993 (/IMP) (8 more)
Cellular response to estradiol stimulus GO:0071392 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Regulation of signal transduction by p53 class mediator GO:1901796 Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
Positive regulation of protein acetylation GO:1901985 Any process that activates or increases the frequency, rate or extent of protein acetylation.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Beta-catenin-TCF complex assembly GO:1904837 The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.	18	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (8 more)
Primitive hemopoiesis GO:0060215 A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.	3	B0R0X6 (/IMP) F6NXN2 (/IMP) Q6DHD0 (/IMP)
Primitive erythrocyte differentiation GO:0060319 Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.	3	B0R0X6 (/IMP) F6NXN2 (/IMP) Q6DHD0 (/IMP)
Nervous system development GO:0007399 The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.	2	Q960X4 (/IMP) Q960X4 (/IMP)
Regulation of gene expression GO:0010468 Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	Q960X4 (/IMP) Q960X4 (/IMP)
Histone exchange GO:0043486 The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.	2	Q960X4 (/IDA) Q960X4 (/IDA)
Negative regulation of neuron apoptotic process GO:0043524 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.	2	Q960X4 (/IMP) Q960X4 (/IMP)
Histone H4 acetylation GO:0043967 The modification of histone H4 by the addition of an acetyl group.	2	Q960X4 (/IMP) Q960X4 (/IMP)
Regulation of synaptic plasticity GO:0048167 A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	2	Q960X4 (/IDA) Q960X4 (/IDA)
Regulation of terminal button organization GO:2000331 Any process that modulates the frequency, rate or extent of terminal button organization.	2	Q960X4 (/IDA) Q960X4 (/IDA)

There are 26 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Swr1 complex GO:0000812 A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Nucleolus GO:0005730 A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Piccolo NuA4 histone acetyltransferase complex GO:0032777 A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
NuA4 histone acetyltransferase complex GO:0035267 A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).	56	Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) Q5RBG4 (/ISS) (46 more)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	47	A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) A0A024R597 (/IDA) (37 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	43	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (33 more)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	41	Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) Q92993 (/TAS) (31 more)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Swr1 complex GO:0000812 A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Transcription factor complex GO:0005667 A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	23	Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) Q8CHK4 (/IDA) (13 more)
Nucleolus GO:0005730 A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Piccolo NuA4 histone acetyltransferase complex GO:0032777 A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	23	Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) Q99MK2 (/IDA) (13 more)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
NuA4 histone acetyltransferase complex GO:0035267 A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).	23	Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) Q8CHK4 (/ISO) (13 more)
NuA4 histone acetyltransferase complex GO:0035267 A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).	20	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (10 more)
Swr1 complex GO:0000812 A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Nucleolus GO:0005730 A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Piccolo NuA4 histone acetyltransferase complex GO:0032777 A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.	18	Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) Q92993 (/IDA) (8 more)
Histone acetyltransferase complex GO:0000123 A protein complex that possesses histone acetyltransferase activity.	2	Q960X4 (/IPI) Q960X4 (/IPI)
Polytene chromosome interband GO:0005705 A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.	2	Q960X4 (/IDA) Q960X4 (/IDA)

Functional Families

There are 25 GO terms relating to "molecular function"

There are 57 GO terms relating to "biological process"

There are 26 GO terms relating to "cellular component"