The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribosomal protein L24e
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: 60S ribosomal protein l24

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
52 P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA)
(42 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
52 P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA)
(42 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
52 P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS)
(42 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
52 P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI) P83731 (/IPI)
(42 more)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
52 P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA)
(42 more)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
52 P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA)
(42 more)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
52 P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC) P83732 (/IC)
(42 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
52 P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS) P83731 (/NAS)
(42 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
SRP-dependent cotranslational protein targeting to membrane GO:0006614
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Mitotic cell cycle checkpoint GO:0007093
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Viral transcription GO:0019083
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Optic nerve development GO:0021554
The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
52 Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP) Q8BP67 (/IMP)
(42 more)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
1 Q8JGR4 (/IMP)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
123 C9JNW5 (/IDA) C9JNW5 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA)
(113 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
123 C9JNW5 (/IDA) C9JNW5 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA) C9JXB8 (/IDA)
(113 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
104 P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA)
(94 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
52 P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA)
(42 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
52 P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA)
(42 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
52 P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA)
(42 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
52 P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS) P83731 (/TAS)
(42 more)
Cytosolic ribosome GO:0022626
A ribosome located in the cytosol.
52 P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA) P83732 (/IDA)
(42 more)
Cytosolic ribosome GO:0022626
A ribosome located in the cytosol.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Polysomal ribosome GO:0042788
A ribosome bound to mRNA that forms part of a polysome.
52 P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA) P83731 (/IDA)
(42 more)
Polysomal ribosome GO:0042788
A ribosome bound to mRNA that forms part of a polysome.
52 Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO) Q8BP67 (/ISO)
(42 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
52 Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP) Q8BP67 (/EXP)
(42 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
52 Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA) Q8BP67 (/IDA)
(42 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
52 P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA) P83731 (/HDA)
(42 more)