The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 46: Peptidyl-prolyl cis-trans isomerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 26 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidyl-prolyl cis-trans isomerase activity GO:0003755
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
14 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 B0BNL2 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI)
(4 more)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
13 Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI)
(3 more)
Peptidyl-prolyl cis-trans isomerase activity GO:0003755
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
12 Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP) Q13526 (/EXP)
(2 more)
Peptidyl-prolyl cis-trans isomerase activity GO:0003755
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
12 Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS)
(2 more)
Peptidyl-prolyl cis-trans isomerase activity GO:0003755
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Cis-trans isomerase activity GO:0016859
Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
12 Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP)
(2 more)
Mitogen-activated protein kinase kinase binding GO:0031434
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase.
12 Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI)
(2 more)
GTPase activating protein binding GO:0032794
Interacting selectively and non-covalently with a GTPase activating protein.
12 Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI)
(2 more)
Tau protein binding GO:0048156
Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
12 Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS) Q13526 (/NAS)
(2 more)
Phosphoserine residue binding GO:0050815
Interacting selectively and non-covalently with a phosphorylated serine residue within a protein.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Phosphothreonine residue binding GO:0050816
Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Phosphothreonine residue binding GO:0050816
Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein.
12 Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI) Q13526 (/IPI)
(2 more)
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Cis-trans isomerase activity GO:0016859
Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
4 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS)
Peptidyl-prolyl cis-trans isomerase activity GO:0003755
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
1 Q9QUR7 (/ISO)
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
1 Q9QUR7 (/IMP)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q9QUR7 (/ISO)
Cis-trans isomerase activity GO:0016859
Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
1 Q9QUR7 (/ISO)
Mitogen-activated protein kinase kinase binding GO:0031434
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase.
1 Q9QUR7 (/ISO)
GTPase activating protein binding GO:0032794
Interacting selectively and non-covalently with a GTPase activating protein.
1 Q9QUR7 (/ISO)
Phosphoserine residue binding GO:0050815
Interacting selectively and non-covalently with a phosphorylated serine residue within a protein.
1 Q9QUR7 (/ISO)
Phosphothreonine residue binding GO:0050816
Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein.
1 Q9QUR7 (/ISO)
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
1 Q9QUR7 (/IPI)

There are 69 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
13 Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP)
(3 more)
Protein peptidyl-prolyl isomerization GO:0000413
The modification of a protein by cis-trans isomerization of a proline residue.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
12 Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI)
(2 more)
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
12 Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP)
(2 more)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
12 Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI) Q13526 (/IGI)
(2 more)
Negative regulation of type I interferon production GO:0032480
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
12 Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP)
(2 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of pathway-restricted SMAD protein phosphorylation GO:0060393
Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of protein localization to nucleus GO:1900180
Any process that modulates the frequency, rate or extent of protein localization to nucleus.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Negative regulation of amyloid-beta formation GO:1902430
Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.
12 Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP) Q13526 (/IMP)
(2 more)
Negative regulation of cell motility GO:2000146
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
5 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q9QUR7 (/ISS)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
5 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q9QUR7 (/ISS)
Negative regulation of amyloid-beta formation GO:1902430
Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.
5 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q9QUR7 (/ISS)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
3 Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q9QUR7 (/ISO)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
1 Q9QUR7 (/ISO)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 B0BNL2 (/IMP)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 Q9QUR7 (/ISO)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
1 Q6PBX1 (/IGI)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9QUR7 (/ISO)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
1 Q9QUR7 (/IMP)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
1 Q9QUR7 (/ISO)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
1 Q9QUR7 (/ISO)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
1 Q9QUR7 (/ISO)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q9QUR7 (/ISO)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
1 Q9QUR7 (/ISO)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
1 B0BNL2 (/IMP)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
1 Q9QUR7 (/ISO)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q9QUR7 (/IMP)
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
1 Q9QUR7 (/ISO)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
1 B0BNL2 (/IMP)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
1 Q9QUR7 (/ISO)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 B0BNL2 (/IMP)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 Q9QUR7 (/ISO)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
1 Q9QUR7 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9QUR7 (/ISO)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
1 Q9QUR7 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q9QUR7 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q9QUR7 (/ISO)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
1 Q9QUR7 (/ISO)
Regulation of pathway-restricted SMAD protein phosphorylation GO:0060393
Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
1 Q9QUR7 (/ISO)
Positive regulation of cell growth involved in cardiac muscle cell development GO:0061051
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
1 B0BNL2 (/IMP)
Positive regulation of cell growth involved in cardiac muscle cell development GO:0061051
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
1 Q9QUR7 (/ISO)
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 Q9QUR7 (/ISO)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q9QUR7 (/IC)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q9QUR7 (/ISO)
Regulation of protein localization to nucleus GO:1900180
Any process that modulates the frequency, rate or extent of protein localization to nucleus.
1 Q9QUR7 (/ISO)
Regulation of intrinsic apoptotic signaling pathway in response to DNA damage GO:1902229
Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
1 Q6PBX1 (/IMP)
Negative regulation of amyloid-beta formation GO:1902430
Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.
1 Q9QUR7 (/ISO)
Negative regulation of cell motility GO:2000146
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
1 Q9QUR7 (/ISO)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
15 B0BNL2 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(5 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
14 B0BNL2 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS) Q13526 (/ISS)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS) Q13526 (/TAS)
(2 more)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
12 Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA) Q13526 (/IDA)
(2 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q4R383 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS) Q5BIN5 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 B0BNL2 (/IDA) Q9QUR7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9QUR7 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9QUR7 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9QUR7 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 B0BNL2 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9QUR7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9QUR7 (/ISO)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
1 Q9QUR7 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 B0BNL2 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q9QUR7 (/ISO)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q9QUR7 (/ISO)
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
1 Q9QUR7 (/ISO)
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