The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleiotrophin/Midkine, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Midkine a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 A0A0B5JK07 (/IPI) A0A0B5JQ06 (/IPI) P12025 (/IPI) P21741 (/IPI) P21741 (/IPI) P21741 (/IPI) P21741 (/IPI) P21741 (/IPI) P21741 (/IPI) P21741 (/IPI)
(3 more)
Chondroitin sulfate binding GO:0035374
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
11 P12025 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
(1 more)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
10 P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS)
Heparan sulfate binding GO:1904399
Interacting selectively and non-covalently with heparan sulfate.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
8 P12025 (/ISS) P48530 (/ISS) P48530 (/ISS) P48531 (/ISS) P48531 (/ISS) Q6P8F3 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Heparan sulfate proteoglycan binding GO:0043395
Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
3 P48531 (/ISS) P48531 (/ISS) Q6P8F3 (/ISS)
Heparan sulfate binding GO:1904399
Interacting selectively and non-covalently with heparan sulfate.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Heparan sulfate proteoglycan binding GO:0043395
Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
2 P48530 (/IDA) P48530 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P12025 (/ISO)
Chondroitin sulfate binding GO:0035374
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
1 P12025 (/IDA)
Heparan sulfate binding GO:1904399
Interacting selectively and non-covalently with heparan sulfate.
1 P12025 (/ISO)

There are 145 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Leukocyte chemotaxis involved in inflammatory response GO:0002232
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
13 P12025 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(3 more)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
13 P12025 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(3 more)
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
13 P12025 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(3 more)
T cell activation involved in immune response GO:0002286
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of leukocyte chemotaxis GO:0002690
Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Negative regulation of ossification GO:0030279
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Regulation of chondrocyte differentiation GO:0032330
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of T cell differentiation GO:0045582
Any process that activates or increases the frequency, rate or extent of T cell differentiation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Regulation of bone remodeling GO:0046850
Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of cartilage development GO:0061036
Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Negative regulation of inflammatory response to wounding GO:0106015
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of inflammatory response to wounding GO:0106016
Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Glial cell projection elongation GO:0106091
The process of creating an elongation or projection from a glial cell.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Negative regulation of epithelial cell apoptotic process GO:1904036
Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996
Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of vascular endothelial cell proliferation GO:1905564
Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of artery morphogenesis GO:1905653
Any process that activates or increases the frequency, rate or extent of artery morphogenesis.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of neural precursor cell proliferation GO:2000179
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Positive regulation of neutrophil extravasation GO:2000391
Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.
12 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(2 more)
Leukocyte chemotaxis involved in inflammatory response GO:0002232
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
11 P12025 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
(1 more)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
11 P12025 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
(1 more)
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
11 P12025 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
(1 more)
Adrenal gland development GO:0030325
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
11 P12025 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
(1 more)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
11 P12025 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
(1 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
10 P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
10 P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
10 P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
10 P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS) P21741 (/ISS)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation of keratinocyte proliferation GO:0010838
Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
10 P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS) P21741 (/NAS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Negative regulation of regulatory T cell differentiation GO:0045590
Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation of smooth muscle cell chemotaxis GO:0071673
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation of leukocyte cell-cell adhesion GO:1903039
Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation blood vessel branching GO:1905555
Any process that activates or increases the frequency, rate or extent of blood vessel branching.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
10 P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA) P21741 (/IDA)
Positive regulation of interleukin-12 secretion GO:2001184
Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Positive regulation of neuron migration GO:2001224
Any process that activates or increases the frequency, rate or extent of neuron migration.
10 P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP) P21741 (/IMP)
Neural tube formation GO:0001841
The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
5 A0A0B5JQ06 (/IMP) A0A1D5NS41 (/IMP) A0A1D5NSV1 (/IMP) E9QIK2 (/IMP) Q9W767 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
5 A0A0B5JK07 (/IMP) P48530 (/IMP) P48530 (/IMP) Q9DDG2 (/IMP) Q9W768 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
5 A0A0B5JQ06 (/IMP) A0A1D5NS41 (/IMP) A0A1D5NSV1 (/IMP) E9QIK2 (/IMP) Q9W767 (/IMP)
Sensory epithelium regeneration GO:0070654
The regrowth of a sensory epithelium following its loss or destruction.
5 A0A0B5JQ06 (/IMP) A0A1D5NS41 (/IMP) A0A1D5NSV1 (/IMP) E9QIK2 (/IMP) Q9W767 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
3 P48531 (/ISS) P48531 (/ISS) Q6P8F3 (/ISS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 A0A0B5JK07 (/IMP) Q9DDG2 (/IMP) Q9W768 (/IMP)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
3 P48531 (/ISS) P48531 (/ISS) Q6P8F3 (/ISS)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
3 P12025 (/IDA) Q9R1S9 (/IDA) Q9R1S9 (/IDA)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
3 P48531 (/ISS) P48531 (/ISS) Q6P8F3 (/ISS)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of keratinocyte proliferation GO:0010838
Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
3 A0A0B5JK07 (/IMP) Q9DDG2 (/IMP) Q9W768 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Negative regulation of regulatory T cell differentiation GO:0045590
Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
3 A0A0B5JK07 (/IMP) Q9DDG2 (/IMP) Q9W768 (/IMP)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of smooth muscle cell chemotaxis GO:0071673
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of leukocyte cell-cell adhesion GO:1903039
Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation blood vessel branching GO:1905555
Any process that activates or increases the frequency, rate or extent of blood vessel branching.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of interleukin-12 secretion GO:2001184
Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Positive regulation of neuron migration GO:2001224
Any process that activates or increases the frequency, rate or extent of neuron migration.
3 P12025 (/ISS) Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
2 P48530 (/IMP) P48530 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 P48530 (/IMP) P48530 (/IMP)
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
2 Q9R1S9 (/IEP) Q9R1S9 (/IEP)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
2 Q9R1S9 (/IDA) Q9R1S9 (/IDA)
Adrenal gland development GO:0030325
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
2 Q9R1S9 (/IDA) Q9R1S9 (/IDA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 Q9R1S9 (/IEP) Q9R1S9 (/IEP)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
2 Q9R1S9 (/ISS) Q9R1S9 (/ISS)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
2 Q9R1S9 (/IEP) Q9R1S9 (/IEP)
Behavioral fear response GO:0001662
An acute behavioral change resulting from a perceived external threat.
1 P12025 (/IMP)
Leukocyte chemotaxis involved in inflammatory response GO:0002232
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
1 P12025 (/ISO)
T cell activation involved in immune response GO:0002286
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
1 P12025 (/IMP)
Positive regulation of leukocyte chemotaxis GO:0002690
Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
1 P12025 (/IMP)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 P12025 (/IMP)
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
1 P12025 (/IDA)
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
1 P12025 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 P12025 (/ISO)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
1 P12025 (/ISO)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P12025 (/ISO)
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
1 P12025 (/ISO)
Positive regulation of keratinocyte proliferation GO:0010838
Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
1 P12025 (/ISO)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 P12025 (/ISO)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
1 P12025 (/IMP)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 P12025 (/ISO)
Dentate gyrus development GO:0021542
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
1 P12025 (/IEP)
Cerebellar granular layer development GO:0021681
The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
1 P12025 (/IMP)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
1 P12025 (/IMP)
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
1 P12025 (/IEP)
Negative regulation of ossification GO:0030279
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 P12025 (/IMP)
Adrenal gland development GO:0030325
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
1 P12025 (/ISO)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 P12025 (/ISO)
Defecation GO:0030421
The expulsion of feces from the rectum.
1 P12025 (/IMP)
Regulation of chondrocyte differentiation GO:0032330
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
1 P12025 (/IMP)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
1 P12025 (/IMP)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
1 P12025 (/IMP)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
1 P12025 (/ISO)
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
1 P12025 (/IMP)
Positive regulation of T cell differentiation GO:0045582
Any process that activates or increases the frequency, rate or extent of T cell differentiation.
1 P12025 (/IMP)
Negative regulation of regulatory T cell differentiation GO:0045590
Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
1 P12025 (/ISO)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
1 P12025 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P12025 (/IMP)
Regulation of bone remodeling GO:0046850
Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
1 P12025 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 P12025 (/IMP)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
1 P12025 (/ISO)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
1 P12025 (/ISO)
Regulation of behavior GO:0050795
Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
1 P12025 (/IMP)
Positive regulation of cartilage development GO:0061036
Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 P12025 (/IMP)
Positive regulation of smooth muscle cell chemotaxis GO:0071673
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.
1 P12025 (/ISO)
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
1 P12025 (/IMP)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 P12025 (/IMP)
Negative regulation of inflammatory response to wounding GO:0106015
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
1 P12025 (/IMP)
Positive regulation of inflammatory response to wounding GO:0106016
Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
1 P12025 (/IMP)
Glial cell projection elongation GO:0106091
The process of creating an elongation or projection from a glial cell.
1 P12025 (/IDA)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1 P12025 (/IMP)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1 P12025 (/IDA)
Positive regulation of leukocyte cell-cell adhesion GO:1903039
Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.
1 P12025 (/ISO)
Negative regulation of epithelial cell apoptotic process GO:1904036
Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.
1 P12025 (/IMP)
Positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996
Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
1 P12025 (/IMP)
Positive regulation blood vessel branching GO:1905555
Any process that activates or increases the frequency, rate or extent of blood vessel branching.
1 P12025 (/ISO)
Positive regulation of vascular endothelial cell proliferation GO:1905564
Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
1 P12025 (/IMP)
Positive regulation of artery morphogenesis GO:1905653
Any process that activates or increases the frequency, rate or extent of artery morphogenesis.
1 P12025 (/IMP)
Positive regulation of neural precursor cell proliferation GO:2000179
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
1 P12025 (/IMP)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
1 P12025 (/ISO)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
1 P12025 (/IMP)
Positive regulation of neutrophil extravasation GO:2000391
Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.
1 P12025 (/IMP)
Positive regulation of interleukin-12 secretion GO:2001184
Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion.
1 P12025 (/ISO)
Positive regulation of neuron migration GO:2001224
Any process that activates or increases the frequency, rate or extent of neuron migration.
1 P12025 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
10 P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS) P21741 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 A0A0B5JK07 (/IDA) Q9DDG2 (/IDA) Q9W768 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9R1S9 (/IDA) Q9R1S9 (/IDA)
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
2 Q9R1S9 (/IDA) Q9R1S9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P12025 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q9W767 (/IDA)
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
1 P12025 (/ISO)
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