The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleiotrophin/Midkine, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Pleiotrophin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 32 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 A0A0B5JW32 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI)
(4 more)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
14 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(4 more)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
13 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(3 more)
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
11 P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS)
(1 more)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
11 P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI)
(1 more)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
11 P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI) P21246 (/IPI)
(1 more)
Chondroitin sulfate binding GO:0035374
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
9 P21782 (/ISS) P21782 (/ISS) P32760 (/ISS) P48532 (/ISS) P48533 (/ISS) P63089 (/ISS) P63089 (/ISS) P79281 (/ISS) P79281 (/ISS)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
9 P21782 (/ISS) P21782 (/ISS) P32760 (/ISS) P48532 (/ISS) P48533 (/ISS) P63089 (/ISS) P63089 (/ISS) P79281 (/ISS) P79281 (/ISS)
Chondroitin sulfate binding GO:0035374
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
9 P21782 (/ISS) P21782 (/ISS) P32760 (/ISS) P48532 (/ISS) P48533 (/ISS) P63089 (/ISS) P63089 (/ISS) P79281 (/ISS) P79281 (/ISS)
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
8 P21782 (/ISS) P21782 (/ISS) P63089 (/ISS) P63089 (/ISS) P63090 (/ISS) P63090 (/ISS) P79281 (/ISS) P79281 (/ISS)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
3 A0A0B5JW32 (/IMP) Q502U6 (/IMP) Q697I0 (/IMP)
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
2 P63089 (/ISO) P63089 (/ISO)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 P63089 (/ISO) P63089 (/ISO)
Glycosaminoglycan binding GO:0005539
Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
2 P63090 (/IDA) P63090 (/IDA)
Glycosaminoglycan binding GO:0005539
Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
2 P63089 (/ISO) P63089 (/ISO)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
2 P63089 (/ISO) P63089 (/ISO)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 P63090 (/IPI) P63090 (/IPI)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 P63089 (/ISO) P63089 (/ISO)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
2 P63089 (/ISO) P63089 (/ISO)
Chondroitin sulfate proteoglycan binding GO:0035373
Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.
2 P63090 (/IPI) P63090 (/IPI)
Chondroitin sulfate proteoglycan binding GO:0035373
Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.
2 P63089 (/ISO) P63089 (/ISO)
Chondroitin sulfate binding GO:0035374
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
2 P63089 (/ISO) P63089 (/ISO)
Vascular endothelial growth factor binding GO:0038085
Interacting selectively and non-covalently with a vascular endothelial growth factor.
2 P63090 (/IPI) P63090 (/IPI)
Vascular endothelial growth factor binding GO:0038085
Interacting selectively and non-covalently with a vascular endothelial growth factor.
2 P63089 (/ISO) P63089 (/ISO)
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
2 P63090 (/IPI) P63090 (/IPI)
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
2 P63089 (/ISO) P63089 (/ISO)
Syndecan binding GO:0045545
Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2 P63090 (/IPI) P63090 (/IPI)
Syndecan binding GO:0045545
Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2 P63089 (/ISO) P63089 (/ISO)
Heparan sulfate binding GO:1904399
Interacting selectively and non-covalently with heparan sulfate.
2 P63090 (/IPI) P63090 (/IPI)
Heparan sulfate binding GO:1904399
Interacting selectively and non-covalently with heparan sulfate.
2 P63089 (/ISO) P63089 (/ISO)

There are 143 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of endothelial cell migration GO:0010594
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
19 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(9 more)
Leukocyte chemotaxis involved in inflammatory response GO:0002232
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of leukocyte chemotaxis GO:0002690
Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of bone mineralization GO:0030501
Any process that activates or increases the frequency, rate or extent of bone mineralization.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Dendrite regeneration GO:0031104
The regrowth of dendrites in response to their loss or damage.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Regulation of myelination GO:0031641
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Dendrite arborization GO:0140059
The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of dendrite development GO:1900006
Any process that activates or increases the frequency, rate or extent of dendrite development.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Negative regulation of long-term synaptic potentiation GO:1900272
Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Regulation of hemopoiesis GO:1903706
Any process that modulates the frequency, rate or extent of hemopoiesis.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Regulation of stem cell population maintenance GO:2000036
Any process that modulates the frequency, rate or extent of stem cell population maintenance.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of stem cell differentiation GO:2000738
Any process that activates or increases the frequency, rate or extent of stem cell differentiation.
17 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(7 more)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
15 P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS) P21246 (/ISS)
(5 more)
Transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185
A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
11 P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS)
(1 more)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
11 P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS)
(1 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
11 P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS)
(1 more)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Ossification involved in bone remodeling GO:0043932
The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
11 P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP) P21246 (/IMP)
(1 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
9 P21782 (/ISS) P21782 (/ISS) P32760 (/ISS) P48532 (/ISS) P48533 (/ISS) P63089 (/ISS) P63089 (/ISS) P79281 (/ISS) P79281 (/ISS)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
8 P21782 (/ISS) P21782 (/ISS) P63089 (/ISS) P63089 (/ISS) P63090 (/ISS) P63090 (/ISS) P79281 (/ISS) P79281 (/ISS)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
8 P21782 (/ISS) P21782 (/ISS) P63089 (/ISS) P63089 (/ISS) P63090 (/ISS) P63090 (/ISS) P79281 (/ISS) P79281 (/ISS)
Ossification involved in bone remodeling GO:0043932
The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
8 P21782 (/ISS) P21782 (/ISS) P63089 (/ISS) P63089 (/ISS) P63090 (/ISS) P63090 (/ISS) P79281 (/ISS) P79281 (/ISS)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
8 P21782 (/ISS) P21782 (/ISS) P63089 (/ISS) P63089 (/ISS) P63090 (/ISS) P63090 (/ISS) P79281 (/ISS) P79281 (/ISS)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
4 P21782 (/ISS) P21782 (/ISS) P79281 (/ISS) P79281 (/ISS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
3 A0A0B5JW32 (/IMP) Q502U6 (/IMP) Q697I0 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 P32760 (/IEP) P63090 (/IEP) P63090 (/IEP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
3 P32760 (/IEP) P63090 (/IEP) P63090 (/IEP)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 P63089 (/IDA) P63089 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
2 P63090 (/IEP) P63090 (/IEP)
Leukocyte chemotaxis involved in inflammatory response GO:0002232
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of leukocyte chemotaxis GO:0002690
Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
2 P63089 (/IMP) P63089 (/IMP)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P63089 (/ISO) P63089 (/ISO)
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
2 P63089 (/IMP) P63089 (/IMP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
2 P63090 (/IEP) P63090 (/IEP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
2 P63089 (/IMP) P63089 (/IMP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P63089 (/ISO) P63089 (/ISO)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
2 P63090 (/IMP) P63090 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
2 P63089 (/ISO) P63089 (/ISO)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
2 P63090 (/IDA) P63090 (/IDA)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
2 P63089 (/ISO) P63089 (/ISO)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 P63090 (/IDA) P63090 (/IDA)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 P63089 (/ISO) P63089 (/ISO)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
2 P63089 (/IMP) P63089 (/IMP)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
2 P63090 (/IMP) P63090 (/IMP)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
2 P63089 (/ISO) P63089 (/ISO)
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
2 P63090 (/IEP) P63090 (/IEP)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
2 P63090 (/IEP) P63090 (/IEP)
Thalamus development GO:0021794
The process in which the thalamus changes over time, from its initial formation to its mature state.
2 P63090 (/IEP) P63090 (/IEP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
2 P63089 (/IDA) P63089 (/IDA)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
2 P63090 (/IEP) P63090 (/IEP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
2 P63090 (/IMP) P63090 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
2 P63089 (/ISO) P63089 (/ISO)
Positive regulation of bone mineralization GO:0030501
Any process that activates or increases the frequency, rate or extent of bone mineralization.
2 P63089 (/IMP) P63089 (/IMP)
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
2 P63090 (/IEP) P63090 (/IEP)
Dendrite regeneration GO:0031104
The regrowth of dendrites in response to their loss or damage.
2 P63090 (/IDA) P63090 (/IDA)
Dendrite regeneration GO:0031104
The regrowth of dendrites in response to their loss or damage.
2 P63089 (/ISO) P63089 (/ISO)
Regulation of myelination GO:0031641
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
2 P63089 (/IMP) P63089 (/IMP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 P63090 (/IEP) P63090 (/IEP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
2 P63090 (/IEP) P63090 (/IEP)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
2 P63089 (/IMP) P63089 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 P63090 (/IEP) P63090 (/IEP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P63090 (/IMP) P63090 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P63089 (/ISO) P63089 (/ISO)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2 P63089 (/ISO) P63089 (/ISO)
Ossification involved in bone remodeling GO:0043932
The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
2 P63089 (/ISO) P63089 (/ISO)
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
2 P63090 (/IEP) P63090 (/IEP)
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
2 P63089 (/IMP) P63089 (/IMP)
Endothelial cell differentiation GO:0045446
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
2 P63090 (/IEP) P63090 (/IEP)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 P63090 (/IMP) P63090 (/IMP)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 P63089 (/ISO) P63089 (/ISO)
Negative regulation of membrane potential GO:0045837
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 P63090 (/IDA) P63090 (/IDA)
Negative regulation of membrane potential GO:0045837
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 P63089 (/ISO) P63089 (/ISO)
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
2 P63089 (/IMP) P63089 (/IMP)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
2 P63089 (/IMP) P63089 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
2 P63090 (/IDA) P63090 (/IDA)
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
2 P63089 (/ISO) P63089 (/ISO)
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
2 P63089 (/ISO) P63089 (/ISO)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
2 P63090 (/IDA) P63090 (/IDA)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
2 P63089 (/ISO) P63089 (/ISO)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 P63090 (/IEP) P63090 (/IEP)
Retinal rod cell differentiation GO:0060221
The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
2 P63090 (/IMP) P63090 (/IMP)
Retinal rod cell differentiation GO:0060221
The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
2 P63089 (/ISO) P63089 (/ISO)
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
2 P63090 (/IMP) P63090 (/IMP)
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
2 P63089 (/ISO) P63089 (/ISO)
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
2 P63090 (/IEP) P63090 (/IEP)
Cellular response to vitamin D GO:0071305
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P63090 (/IEP) P63090 (/IEP)
Negative regulation of mesenchymal cell proliferation GO:0072201
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
2 P63090 (/IDA) P63090 (/IDA)
Negative regulation of mesenchymal cell proliferation GO:0072201
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
2 P63089 (/ISO) P63089 (/ISO)
Dendrite arborization GO:0140059
The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of dendrite development GO:1900006
Any process that activates or increases the frequency, rate or extent of dendrite development.
2 P63089 (/IMP) P63089 (/IMP)
Negative regulation of long-term synaptic potentiation GO:1900272
Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.
2 P63089 (/IMP) P63089 (/IMP)
Regulation of hemopoiesis GO:1903706
Any process that modulates the frequency, rate or extent of hemopoiesis.
2 P63089 (/IMP) P63089 (/IMP)
Response to kainic acid GO:1904373
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Rod bipolar cell differentiation GO:1904389
The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.
2 P63090 (/IEP) P63090 (/IEP)
Response to ciliary neurotrophic factor GO:1904391
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Positive regulation of skeletal muscle acetylcholine-gated channel clustering GO:1904395
Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
2 P63090 (/IDA) P63090 (/IDA)
Positive regulation of skeletal muscle acetylcholine-gated channel clustering GO:1904395
Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
2 P63089 (/ISO) P63089 (/ISO)
Negative regulation of neuromuscular junction development GO:1904397
Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.
2 P63090 (/IDA) P63090 (/IDA)
Negative regulation of neuromuscular junction development GO:1904397
Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.
2 P63089 (/ISO) P63089 (/ISO)
Response to nerve growth factor GO:1990089
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
2 P63090 (/IEP) P63090 (/IEP)
Regulation of stem cell population maintenance GO:2000036
Any process that modulates the frequency, rate or extent of stem cell population maintenance.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2 P63090 (/IDA) P63090 (/IDA)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2 P63089 (/IMP) P63089 (/IMP)
Positive regulation of hepatocyte proliferation GO:2000347
Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2 P63089 (/ISO) P63089 (/ISO)
Positive regulation of stem cell differentiation GO:2000738
Any process that activates or increases the frequency, rate or extent of stem cell differentiation.
2 P63089 (/IMP) P63089 (/IMP)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 P32760 (/ISA)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 P32760 (/IEP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
1 P32760 (/ISA)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 P48533 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 P48532 (/ISS)
Regulation of endothelial cell migration GO:0010594
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
1 P32760 (/IDA)
Neural tube development GO:0021915
The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
1 P32760 (/IEP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 P32760 (/ISA)
Tendon development GO:0035989
The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.
1 P32760 (/IEP)
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
1 P32760 (/IEP)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 P32760 (/IEP)
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
1 P32760 (/IEP)
Dermatome development GO:0061054
The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
1 P32760 (/IEP)
Sclerotome development GO:0061056
The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
1 P32760 (/IEP)

There are 28 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
11 P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS) P21246 (/TAS)
(1 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
11 P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA) P21246 (/IDA)
(1 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
9 P21782 (/ISS) P21782 (/ISS) P32760 (/ISS) P48532 (/ISS) P48533 (/ISS) P63089 (/ISS) P63089 (/ISS) P79281 (/ISS) P79281 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 P63089 (/IDA) P63089 (/IDA) P63090 (/IDA) P63090 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 P21782 (/ISS) P21782 (/ISS) P79281 (/ISS) P79281 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P63089 (/ISO) P63089 (/ISO)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
2 P63090 (/IDA) P63090 (/IDA)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
2 P63089 (/ISO) P63089 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P63089 (/ISO) P63089 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P63090 (/IDA) P63090 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P63089 (/ISO) P63089 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 P63089 (/ISO) P63089 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P63090 (/IDA) P63090 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P63089 (/ISO) P63089 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P63090 (/IDA) P63090 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P63089 (/ISO) P63089 (/ISO)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
2 P63089 (/TAS) P63089 (/TAS)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
2 P63090 (/IDA) P63090 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
2 P63089 (/ISO) P63089 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 P63089 (/ISO) P63089 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 P63090 (/IDA) P63090 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 P63089 (/ISO) P63089 (/ISO)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
2 P63090 (/IDA) P63090 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
2 P63089 (/ISO) P63089 (/ISO)
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
2 P63090 (/IDA) P63090 (/IDA)
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
2 P63089 (/ISO) P63089 (/ISO)
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