The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ADC-like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Formate dehydrogenase subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
21 P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI) P07658 (/IPI)
(11 more)
Molybdenum ion binding GO:0030151
Interacting selectively and non-covalently with molybdenum (Mo) ions.
21 P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA)
(11 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
21 P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA)
(11 more)
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
2 Q74GA2 (/ISS) Q74GA2 (/ISS)
Formate dehydrogenase (NAD+) activity GO:0008863
Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.
2 Q604G7 (/ISS) Q608U8 (/ISS)
Oxidoreductase activity, acting on NAD(P)H GO:0016651
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2 Q74FU6 (/IDA) Q74FU6 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formate oxidation GO:0015944
The chemical reactions and pathways by which formate is converted to CO2.
21 P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA)
(11 more)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
2 Q74GA2 (/ISS) Q74GA2 (/ISS)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
2 Q74FU6 (/TAS) Q74FU6 (/TAS)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 Q604G7 (/ISS) Q608U8 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA) P07658 (/IDA)
(11 more)
Formate dehydrogenase complex GO:0009326
An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).
2 Q604G7 (/ISS) Q608U8 (/ISS)
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