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CATH Superfamily 2.20.25.190

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Transcription elongation factor 1 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
 8 P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 3 G4MN17 (/ISS) G4MN17 (/ISS) G4MN17 (/ISS)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
 1 Q54KR5 (/ISS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 1 O13868 (/ISM)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
 8 P36053 (/IGI) P36053 (/IGI) P36053 (/IGI) P36053 (/IGI) P36053 (/IGI) P36053 (/IGI) P36053 (/IGI) P36053 (/IGI)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
 8 P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP)
Chromatin-mediated maintenance of transcription GO:0048096
Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.
 8 P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP) P36053 (/IMP)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
 4 G4MN17 (/ISS) G4MN17 (/ISS) G4MN17 (/ISS) Q54KR5 (/ISS)
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
 3 G4MN17 (/ISS) G4MN17 (/ISS) G4MN17 (/ISS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
 3 G4MN17 (/ISS) G4MN17 (/ISS) G4MN17 (/ISS)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
 1 O13868 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 9 O13868 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA) P36053 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 8 P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA)
Transcription elongation factor complex GO:0008023
Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
 8 P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA) P36053 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 4 G4MN17 (/ISS) G4MN17 (/ISS) G4MN17 (/ISS) Q54KR5 (/ISS)