CATH Superfamily 2.20.25.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 5: DNA-directed RNA polymerase subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
|
1 | Q9Y2Y1 (/TAS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Termination of RNA polymerase III transcription GO:0006386
The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.
|
8 | Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) |
|
Termination of RNA polymerase III transcription GO:0006386
The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.
|
8 | Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) |
|
TRNA transcription by RNA polymerase III GO:0042797
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
|
8 | Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) |
|
TRNA transcription by RNA polymerase III GO:0042797
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
|
8 | Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) Q04307 (/IMP) |
|
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
|
1 | Q9Y2Y1 (/TAS) |
|
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
1 | Q9Y2Y1 (/TAS) |
|
Hematopoietic stem cell homeostasis GO:0061484
Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.
|
1 | Q6DGU0 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
9 | Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q04307 (/TAS) Q9Y2Y1 (/TAS) |
|
RNA polymerase III complex GO:0005666
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
|
8 | Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) Q04307 (/IDA) |
|
RNA polymerase III complex GO:0005666
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
|
1 | Q9Y2Y1 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9Y2Y1 (/TAS) |
