The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SET domain
".
FunFam 98: Histone-lysine N-methyltransferase, H3 lysine-9 sp...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8GZB6 (/IPI) |
|
Methyl-CpG binding GO:0008327
Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide.
|
1 | Q8GZB6 (/IDA) |
|
Double-stranded methylated DNA binding GO:0010385
Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
|
1 | Q8GZB6 (/IDA) |
|
Methyl-CpNpG binding GO:0010428
Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.
|
1 | Q8GZB6 (/IDA) |
|
Methyl-CpNpN binding GO:0010429
Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.
|
1 | Q8GZB6 (/IDA) |
|
Histone methyltransferase activity (H3-K9 specific) GO:0046974
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein.
|
1 | Q8GZB6 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Maintenance of DNA methylation GO:0010216
Any process involved in maintaining the methylation state of a nucleotide sequence.
|
1 | Q8GZB6 (/IDA) |
|
Histone methylation GO:0016571
The modification of histones by addition of methyl groups.
|
1 | Q8GZB6 (/IDA) |
|
Peptidyl-lysine methylation GO:0018022
The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
|
1 | Q8GZB6 (/IDA) |
|
Histone H3-K9 methylation GO:0051567
The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
|
1 | Q8GZB6 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.