The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SET domain
".
FunFam 42: Variant-silencing SET protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8IE95 (/IPI) Q8IE95 (/IPI) |
|
Histone-lysine N-methyltransferase activity GO:0018024
Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Histone methyltransferase activity (H3-K36 specific) GO:0046975
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Histone H3-K36 methylation GO:0010452
The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Evasion or tolerance of host immune response GO:0020012
Any process, either active or passive, by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Antigenic variation GO:0020033
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
|
2 | Q8IE95 (/IMP) Q8IE95 (/IMP) |
|
Histone H3-K36 trimethylation GO:0097198
The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
|
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
2 | Q8IE95 (/IDA) Q8IE95 (/IDA) |
