The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Spindle assembly abnormal protein 6, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Spindle assembly abnormal protein 6 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q6UVJ0 (/IPI) Q6UVJ0 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centriole replication GO:0007099
The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
6 Q5ZMV2 (/ISS) Q6NRG6 (/ISS) Q6NRG6 (/ISS) Q7ZVT3 (/ISS) Q7ZVT3 (/ISS) Q80UK7 (/ISS)
Centrosome duplication GO:0051298
The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
4 Q6UVJ0 (/IMP) Q6UVJ0 (/IMP) Q7ZVT3 (/IMP) Q7ZVT3 (/IMP)
Nuclear division GO:0000280
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
2 Q7ZVT3 (/IMP) Q7ZVT3 (/IMP)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
2 Q7ZVT3 (/IMP) Q7ZVT3 (/IMP)
Centriole replication GO:0007099
The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
2 Q6UVJ0 (/IMP) Q6UVJ0 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q7ZVT3 (/IMP) Q7ZVT3 (/IMP)
Embryonic cleavage GO:0040016
The first few specialized divisions of an activated animal egg.
2 Q7ZVT3 (/IMP) Q7ZVT3 (/IMP)
Centriole replication GO:0007099
The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
1 Q80UK7 (/ISO)
Centrosome duplication GO:0051298
The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
1 Q80UK7 (/ISO)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
5 Q5ZMV2 (/ISS) Q6NRG6 (/ISS) Q6NRG6 (/ISS) Q7ZVT3 (/ISS) Q7ZVT3 (/ISS)
Deuterosome GO:0098536
A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.
5 Q5ZMV2 (/ISS) Q6UVJ0 (/ISS) Q6UVJ0 (/ISS) Q7ZVT3 (/ISS) Q7ZVT3 (/ISS)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
4 Q6UVJ0 (/IDA) Q6UVJ0 (/IDA) Q7ZVT3 (/IDA) Q7ZVT3 (/IDA)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
3 Q6UVJ0 (/IDA) Q6UVJ0 (/IDA) Q80UK7 (/IDA)
Deuterosome GO:0098536
A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.
3 Q6NRG6 (/IDA) Q6NRG6 (/IDA) Q80UK7 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q6UVJ0 (/NAS) Q6UVJ0 (/NAS)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
2 Q6UVJ0 (/IDA) Q6UVJ0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q6UVJ0 (/IDA) Q6UVJ0 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q80UK7 (/ISO)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
1 Q80UK7 (/ISO)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
1 Q80UK7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q80UK7 (/ISO)
CATH-Gene3D is a Global Biodata Core Resource Learn more...