The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAC domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: NAC transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 Q53NF7 (/IPI) Q75HE5 (/IPI) Q75HE5 (/IPI) Q75HE5 (/IPI) Q75HE5 (/IPI) Q7F2L3 (/IPI) Q7F2L3 (/IPI) Q8H115 (/IPI) Q8H115 (/IPI) Q9C598 (/IPI)
(1 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
10 O49255 (/ISS) O49255 (/ISS) Q39013 (/ISS) Q39013 (/ISS) Q39013 (/ISS) Q8H115 (/ISS) Q8H115 (/ISS) Q9CAR0 (/ISS) Q9CAR0 (/ISS) Q9CAR0 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
8 K4BNG7 (/IDA) K4BWV2 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA) Q7F2L3 (/IDA) Q7F2L3 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 Q75HE5 (/IPI) Q75HE5 (/IPI) Q75HE5 (/IPI) Q75HE5 (/IPI)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
3 Q39013 (/IPI) Q39013 (/IPI) Q39013 (/IPI)
Protein histidine kinase binding GO:0043424
Interacting selectively and non-covalently with protein histidine kinase.
2 Q9C598 (/IPI) Q9C598 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q8H115 (/IPI) Q8H115 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q8H115 (/IPI) Q8H115 (/IPI)

There are 32 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
8 Q53NF7 (/IDA) Q7F2L3 (/IDA) Q7F2L3 (/IDA) Q9C598 (/IDA) Q9C598 (/IDA) Q9CAR0 (/IDA) Q9CAR0 (/IDA) Q9CAR0 (/IDA)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
7 O49255 (/IMP) O49255 (/IMP) Q9C598 (/IMP) Q9C598 (/IMP) Q9CAR0 (/IMP) Q9CAR0 (/IMP) Q9CAR0 (/IMP)
Positive regulation of response to salt stress GO:1901002
Any process that activates or increases the frequency, rate or extent of response to salt stress.
7 Q53NF7 (/IMP) Q75HE5 (/IMP) Q75HE5 (/IMP) Q75HE5 (/IMP) Q75HE5 (/IMP) Q7F2L3 (/IMP) Q7F2L3 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6 K4BNG7 (/IDA) K4BWV2 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA) Q75HE5 (/IDA)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
6 K4BNG7 (/IMP) K4BWV2 (/IMP) O49255 (/IMP) O49255 (/IMP) Q9C598 (/IMP) Q9C598 (/IMP)
Positive regulation of response to water deprivation GO:1902584
Any process that activates or increases the frequency, rate or extent of response to water deprivation.
6 Q75HE5 (/IMP) Q75HE5 (/IMP) Q75HE5 (/IMP) Q75HE5 (/IMP) Q7F2L3 (/IMP) Q7F2L3 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
5 Q39013 (/IEP) Q39013 (/IEP) Q39013 (/IEP) Q9C598 (/IEP) Q9C598 (/IEP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
3 Q39013 (/IMP) Q39013 (/IMP) Q39013 (/IMP)
Positive regulation of leaf senescence GO:1900057
Any process that activates or increases the frequency, rate or extent of leaf senescence.
3 Q9CAR0 (/IMP) Q9CAR0 (/IMP) Q9CAR0 (/IMP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 Q8H115 (/IMP) Q8H115 (/IMP)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
2 Q9C598 (/IMP) Q9C598 (/IMP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 Q7F2L3 (/IMP) Q7F2L3 (/IMP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 Q9C598 (/IEP) Q9C598 (/IEP)
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
2 Q9C598 (/IMP) Q9C598 (/IMP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2 Q9C598 (/IEP) Q9C598 (/IEP)
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
2 Q9C598 (/IEP) Q9C598 (/IEP)
Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
2 Q9C598 (/IEP) Q9C598 (/IEP)
Multidimensional cell growth GO:0009825
The process in which a cell irreversibly increases in size in two or three
2 O49255 (/IMP) O49255 (/IMP)
Fruit ripening GO:0009835
An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.
2 O49255 (/IMP) O49255 (/IMP)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
2 O49255 (/IMP) O49255 (/IMP)
Regulation of photomorphogenesis GO:0010099
Any process that modulates the rate or extent of photomorphogenesis.
2 Q9C598 (/IMP) Q9C598 (/IMP)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
2 K4BNG7 (/IEP) K4BWV2 (/IEP)
Glucosinolate metabolic process GO:0019760
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
2 Q8H115 (/IMP) Q8H115 (/IMP)
Regulation of reproductive fruiting body development GO:0031155
Any process that modulates the frequency, rate or extent of reproductive fruiting body development.
2 K4BNG7 (/IMP) K4BWV2 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9C598 (/IDA) Q9C598 (/IDA)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
2 Q7F2L3 (/IMP) Q7F2L3 (/IMP)
Regulation of defense response to fungus GO:1900150
Any process that modulates the frequency, rate or extent of defense response to fungus.
2 Q7F2L3 (/IMP) Q7F2L3 (/IMP)
Response to absence of light GO:0009646
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
1 K4BNG7 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 K4BNG7 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 K4BNG7 (/IMP)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
1 K4BNG7 (/IDA)
Abscisic acid homeostasis GO:1902265
Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.
1 K4BNG7 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 O49255 (/IDA) O49255 (/IDA) Q53NF7 (/IDA) Q7F2L3 (/IDA) Q7F2L3 (/IDA) Q9C598 (/IDA) Q9C598 (/IDA) Q9CAR0 (/IDA) Q9CAR0 (/IDA) Q9CAR0 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q8H115 (/IDA) Q8H115 (/IDA)
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