The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAC domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: NAC domain-containing protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
17 F4HYV5 (/ISS) O65508 (/ISS) O65508 (/ISS) Q84WP6 (/ISS) Q9C878 (/ISS) Q9C878 (/ISS) Q9FH59 (/ISS) Q9FWX2 (/ISS) Q9LPI7 (/ISS) Q9LVA1 (/ISS)
(7 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 A9PDI0 (/IPI) B9GIS7 (/IPI) F4HYV5 (/IPI) O65508 (/IPI) O65508 (/IPI) Q84WP6 (/IPI) Q9FH59 (/IPI) Q9FWX2 (/IPI) Q9MA17 (/IPI) Q9MA17 (/IPI)
(2 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
7 F4HYV5 (/ISS) O65508 (/ISS) O65508 (/ISS) Q9FH59 (/ISS) Q9FWX2 (/ISS) Q9SL41 (/ISS) Q9SL41 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
5 Q9C878 (/IDA) Q9C878 (/IDA) Q9LPI7 (/IDA) Q9LVA1 (/IDA) Q9LVA1 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
4 O65508 (/IPI) O65508 (/IPI) Q9SL41 (/IPI) Q9SL41 (/IPI)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 Q9LVA1 (/IDA) Q9LVA1 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q9LVA1 (/IDA) Q9LVA1 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q9SL41 (/IPI) Q9SL41 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 B9GIS7 (/IPI)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
9 F4HYV5 (/IMP) O65508 (/IMP) O65508 (/IMP) Q9FH59 (/IMP) Q9FWX2 (/IMP) Q9MA17 (/IMP) Q9MA17 (/IMP) Q9SL41 (/IMP) Q9SL41 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
9 F4HYV5 (/TAS) O65508 (/TAS) O65508 (/TAS) Q9FH59 (/TAS) Q9FWX2 (/TAS) Q9LVA1 (/TAS) Q9LVA1 (/TAS) Q9SL41 (/TAS) Q9SL41 (/TAS)
Xylem vessel member cell differentiation GO:0048759
The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
9 F4HYV5 (/IMP) O65508 (/IMP) O65508 (/IMP) Q9FH59 (/IMP) Q9FWX2 (/IMP) Q9LVA1 (/IMP) Q9LVA1 (/IMP) Q9SL41 (/IMP) Q9SL41 (/IMP)
Plant-type secondary cell wall biogenesis GO:0009834
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
8 Q84WP6 (/IMP) Q9C878 (/IMP) Q9C878 (/IMP) Q9LPI7 (/IMP) Q9M274 (/IMP) Q9MA17 (/IMP) Q9MA17 (/IMP) Q9SV87 (/IMP)
Xylem vessel member cell differentiation GO:0048759
The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
7 F4HYV5 (/ISS) O65508 (/ISS) O65508 (/ISS) Q9FH59 (/ISS) Q9FWX2 (/ISS) Q9SL41 (/ISS) Q9SL41 (/ISS)
Positive regulation of secondary cell wall biogenesis GO:1901348
Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.
7 F4HYV5 (/IMP) O65508 (/IMP) O65508 (/IMP) Q9FH59 (/IMP) Q9FWX2 (/IMP) Q9SL41 (/IMP) Q9SL41 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 Q84WP6 (/IDA) Q9LPI7 (/IDA) Q9LVA1 (/IDA) Q9LVA1 (/IDA) Q9M274 (/IDA)
Root cap development GO:0048829
The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
5 Q9C878 (/IMP) Q9C878 (/IMP) Q9MA17 (/IMP) Q9MA17 (/IMP) Q9SV87 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 Q9C878 (/IEP) Q9C878 (/IEP) Q9SV87 (/IEP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 Q9C878 (/IMP) Q9C878 (/IMP) Q9SV87 (/IMP)
Regionalization GO:0003002
The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
2 Q9MA17 (/IMP) Q9MA17 (/IMP)
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
2 Q9LVA1 (/IDA) Q9LVA1 (/IDA)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
2 Q9LVA1 (/IEP) Q9LVA1 (/IEP)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
2 Q9LVA1 (/IEP) Q9LVA1 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
2 Q9LVA1 (/IEP) Q9LVA1 (/IEP)
Response to brassinosteroid GO:0009741
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
2 Q9LVA1 (/IEP) Q9LVA1 (/IEP)
Fruit dehiscence GO:0010047
The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
2 Q84WP6 (/IMP) Q9LPI7 (/IMP)
Xylem development GO:0010089
The formation of the principal water-conducting tissue of a vascular plant.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Response to chitin GO:0010200
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
2 Q9SL41 (/IEP) Q9SL41 (/IEP)
Positive regulation of cell fate commitment GO:0010455
Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
2 Q9MA17 (/IMP) Q9MA17 (/IMP)
Regulation of cell wall macromolecule metabolic process GO:0010981
Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Positive regulation of programmed cell death GO:0043068
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Xylan metabolic process GO:0045491
The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Metaxylem development GO:0090058
The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Callus formation GO:1990110
The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
2 Q9SL41 (/IEP) Q9SL41 (/IEP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q5Z6B6 (/ISS)
Plant-type secondary cell wall biogenesis GO:0009834
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
1 Q84WP6 (/IDA)
Plant-type secondary cell wall biogenesis GO:0009834
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
1 Q5Z6B6 (/ISS)
Root cap development GO:0048829
The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
1 Q5Z6B6 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 O65508 (/IDA) O65508 (/IDA) Q9LPI7 (/IDA) Q9LVA1 (/IDA) Q9LVA1 (/IDA) Q9MA17 (/IDA) Q9MA17 (/IDA)
Secondary cell wall GO:0009531
A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.
2 Q9LVA1 (/IMP) Q9LVA1 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5Z6B6 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9M274 (/IDA)