The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peptide methionine sulfoxide reductase.
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Peptide methionine sulfoxide reductase MsrB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptide-methionine (R)-S-oxide reductase activity GO:0033743
Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
110 P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA)
(100 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
107 P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA)
(97 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
107 P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA)
(97 more)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein repair GO:0030091
The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.
107 P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA)
(97 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
13 Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP)
(3 more)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
13 Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP)
(3 more)
Response to hypochlorite GO:1901530
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.
13 Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP) Q9I016 (/IMP)
(3 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q0DC89 (/IDA) Q0DC89 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q9C8M2 (/IEP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
107 P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA) P0A746 (/IDA)
(97 more)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 Q0DC89 (/IDA) Q0DC89 (/IDA) Q9C8M2 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q9C8M2 (/TAS)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q9C8M2 (/IDA)
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