The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TonB-dependent receptor, plug domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Catecholate siderophore TonB-dependent receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
31 P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI)
(21 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
31 P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI)
(21 more)
Toxic substance binding GO:0015643
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
31 P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP)
(21 more)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
31 P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI)
(21 more)
Virion binding GO:0046790
Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope.
31 P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP)
(21 more)
Cofactor binding GO:0048037
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
31 P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI) P06971 (/IPI)
(21 more)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
5 Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP) Q9I648 (/IMP)
Siderophore uptake transmembrane transporter activity GO:0015344
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).
4 Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP)
Ferrichrome transmembrane transporter activity GO:0042929
Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
1 Q9I648 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Siderophore transport GO:0015891
The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
28 P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP)
(18 more)
Microcin transport GO:0042884
The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
24 P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP) P75780 (/IMP)
(14 more)
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
5 Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP) Q9I116 (/IMP) Q9I648 (/IMP)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
2 Q0WI86 (/EXP) Q0WI86 (/EXP)
Ferrichrome import into cell GO:0042928
A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
1 Q9I648 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell outer membrane GO:0009279
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
55 P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA) P06971 (/IDA)
(45 more)
Cell outer membrane GO:0009279
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
31 P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP) P06971 (/IMP)
(21 more)
Outer membrane GO:0019867
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
5 Q9I116 (/IDA) Q9I116 (/IDA) Q9I116 (/IDA) Q9I116 (/IDA) Q9I648 (/IDA)
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