The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
E3 ubiquitin-protein ligase SopA
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Pentapeptide repeat protein MfpA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA topoisomerase (ATP-hydrolyzing) inhibitor activity GO:0008657
Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
10 O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
10 O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI) O50390 (/IPI)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
10 O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA) O50390 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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