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CATH Superfamily 2.130.10.30

Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1
375
3D
 4o2wD00 - 63.8
2
E3 ubiquitin-protein ligase MYCBP2 isoform X1
329 - - 48.4
3
E3 ubiquitin-protein ligase HERC2 isoform X1
221
3D
 3kciA00 - 65.8
4
E3 ubiquitin-protein ligase HERC2 isoform X2
210 - - 73.1
5
E3 ubiquitin-protein ligase MYCBP2 isoform X1
190 - - 29.2
6
E3 ubiquitin-protein ligase HERC2 isoform X1
190
3D
 4l1mC00 - 91.3
7
E3 ubiquitin-protein ligase UBR5 isoform X2
155 - - 75.7
8
regulator of chromosome condensation isoform X1
151
3D
 5tbkP00 - 47.8
9
Regulator of chromosome condensation 2
132 - - 70.0
10
RCC1 and BTB domain-containing protein 1 isoform X2
116 - - 52.1
11
inhibitor of Bruton tyrosine kinase isoform X2
112 - - 73.3
12
probable E3 ubiquitin-protein ligase HERC3 isoform X1
105 - - 69.8
13
Retinitis pigmentosa GTPase regulator isoform 1
104
3D
 4qamA00 - 82.2
14
probable E3 ubiquitin-protein ligase HERC4 isoform X1
97 - - 22.9
15
alsin isoform X1
95 - - 41.4
16
E3 ubiquitin-protein ligase MYCBP2 isoform X2
84 - - 52.8
17
Serine/threonine-protein kinase Nek8
80 - - 83.5
18
probable E3 ubiquitin-protein ligase HERC3 isoform X1
80 - - 35.0
19
alsin isoform X1
72 - - 37.6
20
serine/threonine-protein kinase Nek8
69 - - 45.4
21
serine/threonine-protein kinase Nek9 isoform X2
63 - - 42.6
22
RCC2 isoform 1
54 - - 72.5
23
serine/threonine-protein kinase Nek9 isoform X2
46 - - 34.3
24
RCC1-like G exchanging factor-like protein
41 - - 45.6
25
HECT and RLD domain containing E3 ubiquitin protein ligase 5
35 - - 70.5
45
Ultraviolet-B receptor UVR8
35
3D
 6dd7D00 - 23.5
26
RCC1-like G exchanging factor-like protein
21 - - 25.7
27
Protein FMP25, mitochondrial
21 - - 77.5
28
PH, RCC1 and FYVE domains-containing protein 1
21 - - 68.4
29
Secretion-regulating guanine nucleotide exchange factor
19 - - 35.7
33
RCC1 and BTB domain-containing protein 2
18 - - 31.1
32
Serine/threonine-protein kinase Nek8
18 - - 47.4
31
PH, RCC1 and FYVE domains-containing protein 1
18 - - 58.3
30
Secretion-regulating guanine nucleotide exchange factor
18 - - 41.8
34
HECT and RLD domain containing E3 ubiquitin protein ligase 4
17 - - 10.2
35
Putative regulator of chromosome condensation
16 - - 10.6
36
Guanidine nucleotide exchange factor
15 - - 9.3
38
RCC1 and BTB domain-containing protein 2
15 - - 39.1
37
Inhibitor of Bruton tyrosine kinase
15 - - 23.9
41
Guanine nucleotide exchange factor SRM1
15
3D
 5t94A00 - 20.0
39
probable E3 ubiquitin-protein ligase HERC4 isoform X3
14 - - 12.6
40
Guanidine nucleotide exchange factor
14 - - 10.1
43
Guanidine nucleotide exchange factor
13 - - 13.4
42
Guanidine nucleotide exchange factor
13 - - 15.2
44
Serine/threonine-protein kinase-like protein CR4
11 - - 44.4
53
Regulator of chromosome condensation
10
3D
 3mvdL00 - 10.3
46
Uncharacterized protein, isoform C
10 - - 13.9
51
Highwire, isoform B
9 - - 69.2
48
YLR077W-like protein
9 - - 5.1
49
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
9 - - 39.6
50
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
9 - - 9.2
47
Regulator of chromosome condensation
RCC1
9 - - 66.8
55
SCF-associated factor 1
8 - - 7.0
52
RCC1 domain containing 1
8 - - 18.2
54
Scf associated factor
8 - - 0.7
58
Regulator of chromosome condensation
7 - - 16.2
61
E3 ubiquitin-protein ligase UBR5
7 - - 7.2
57
RCC1-like G exchanging factor-like protein
7 - - 23.5
59
Alpha tubulin suppressor
7 - - 1.5
60
Regulator of chromosome condensation
7 - - 16.1
56
RCC1 domain containing 1
7 - - 20.0
66
Putative receptor protein kinase CRINKLY4
6 - - 13.4
62
Regulator of chromosome condensation
RCC1
6 - - 37.3
64
RCC1 domain-containing protein RUG3, mitochondrial
6 - - 16.4
65
NEK
NEver in mitosis Kinase
6 - - 16.8
63
GG11698
6 - - 49.3
71
Claret, isoform A
5 - - 72.2
68
Hect domain and RLD 3
5 - - 15.0
69
Serine/threonine-protein kinase-like protein CR4
5 - - 4.1
67
RCC1 domain-containing protein RUG3, mitochondrial
5 - - 13.2
70
SD05384p
5 - - 7.8
76
E3 ubiquitin-protein ligase hyd
4 - - 1.1
78
Serine/threonine-protein kinase Nek8
4 - - 14.5
74
Regulator of chromosome condensation, putative
4 - - 0.0
80
E3 ubiquitin-protein ligase rpm-1
4 - - 42.6
77
Highwire, isoform B
4 - - 2.6
79
Guanidine nucleotide exchange factor
4 - - 6.3
72
Regulator of chromosome condensation, putative
4 - - 0.0
73
Regulator of chromosome condensation, putative
4 - - 0.0
75
SCF-associated factor 1
4 - - 10.4
85
BTB/POZ domain/Regulator of chromosome condensation
RCC1
3 - - 32.3
84
E3 ubiquitin-protein ligase rpm-1
3 - - 14.8
82
Related to FMP25-mitochondrial inner membrane protein involved in assembly of cytochrome bc1 complex
3 - - 8.7
83
3 - - 1.3
81
Regulator of chromosome condensation
RCC1
3 - - 10.1
86
BTB/POZ domain/Regulator of chromosome condensation
RCC1
3 - - 32.5
101
2 - - 24.2
96
2 - - 27.9
98
E3 ubiquitin-protein ligase MYCBP2-like Protein
2 - - 32.5
119
Serine/threonine-protein kinase Nek8-like Protein
2 - - 34.1
107
2 - - 0.0
87
2 - - 38.4
116
Uncharacterized protein
2 - - 3.0
110
2 - - 0.0
112
2 - - 0.0
108
2 - - 0.0
102
2 - - 29.5
89
2 - - 0.0
115
Serine/threonine-protein kinase-like protein CCR1
2 - - 0.0
91
2 - - 37.2
117
2 - - 39.5
92
Uncharacterized protein
2 - - 1.5
105
2 - - 9.5
111
2 - - 0.8
118
2 - - 39.0
113
2 - - 2.8
100
2 - - 18.1
94
2 - - 4.5
109
E3 ubiquitin-protein ligase HERC2
2 - - 0.0
99
Uncharacterized protein
2 - - 10.6
90
2 - - 0.0
93
Uncharacterized protein
2 - - 4.3
114
NimA-like kinase
2 - - 1.8
104
2 - - 3.4
103
2 - - 26.4
97
2 - - 34.5
95
RCC1 Chromatin-associated guanine nucleotide exchange factor for Ran
Eurofung
2 - - 0.0
106
2 - - 12.1
88
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
2 - - 0.0
127
1 - - 0.0
153
1 - - 0.0
160
1 - - 0.0
180
1 - - 0.0
136
1 - - 0.0
144
1 - - 0.0
177
1 - - 0.0
151
1 - - 0.0
138
1 - - 0.0
137
1 - - 0.0
170
1 - - 0.0
182
1 - - 0.0
142
1 - - 0.0
167
1 - - 0.0
128
1 - - 0.0
155
1 - - 0.0
130
1 - - 0.0
163
1 - - 0.0
175
1 - - 0.0
140
Protein pim1
1 - - 0.0
181
1 - - 0.0
154
1 - - 0.0
122
1 - - 0.0
158
1 - - 0.0
132
1 - - 0.0
125
1 - - 0.0
165
1 - - 0.0
147
1 - - 0.0
149
1 - - 0.0
173
1 - - 0.0
156
1 - - 0.0
139
1 - - 0.0
129
1 - - 0.0
168
1 - - 0.0
135
1 - - 0.0
145
1 - - 0.0
178
1 - - 0.0
124
1 - - 0.0
152
1 - - 0.0
120
1 - - 0.0
171
1 - - 0.0
161
1 - - 0.0
126
1 - - 0.0
176
1 - - 0.0
150
1 - - 0.0
131
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
174
1 - - 0.0
143
1 - - 0.0
169
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
172
1 - - 0.0
121
1 - - 0.0
179
1 - - 0.0
133
ABR238Wp
1 - - 0.0
123
1 - - 0.0
166
1 - - 0.0
141
Uncharacterized protein
1 - - 0.0
134
1 - - 0.0
146
1 - - 0.0
164
1 - - 0.0
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