The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kelch-type beta propeller
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 49: Cell polarity protein (Tea1)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
3 G5EAY1 (/IMP) G5EAY1 (/IMP) G5EAY1 (/IMP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Bipolar cell growth GO:0042815
The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
3 G5EAY1 (/IMP) G5EAY1 (/IMP) G5EAY1 (/IMP)
Activation of bipolar cell growth GO:0051519
Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Regulation of microtubule cytoskeleton organization GO:0070507
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 G5EAY1 (/IMP) G5EAY1 (/IMP) G5EAY1 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Division septum GO:0000935
A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Tea1 cell-end complex GO:0031500
A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Spitzenkorper GO:0031521
Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
3 G5EAY1 (/IDA) G5EAY1 (/IDA) G5EAY1 (/IDA)
Cell cortex of cell tip GO:0051285
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
3 G5EAY1 (/IDA) G5EAY1 (/IDA) G5EAY1 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
3 G5EI23 (/ISS) G5EI23 (/ISS) G5EI23 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q7M3S9 (/TAS)
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