The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kelch-type beta propeller
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Muskelin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
7 O89050 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q9UL63 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O89050 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 O89050 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q99PV3 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O89050 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of receptor internalization GO:0002090
Any process that modulates the frequency, rate or extent of receptor internalization.
7 O89050 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q9UL63 (/ISS)
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Regulation of receptor internalization GO:0002090
Any process that modulates the frequency, rate or extent of receptor internalization.
1 Q99PV3 (/IMP)
Regulation of receptor internalization GO:0002090
Any process that modulates the frequency, rate or extent of receptor internalization.
1 O89050 (/ISO)
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
1 O89050 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q9UL63 (/NAS)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 O89050 (/IMP)
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
1 O89050 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
7 Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q5RB35 (/ISS) Q99PV3 (/ISS) Q9UL63 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O89050 (/IDA) Q9UL63 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O89050 (/IDA) Q99PV3 (/IDA)
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
1 Q9UL63 (/IDA)
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
1 O89050 (/ISO)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
1 O89050 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O89050 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O89050 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O89050 (/ISO)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 O89050 (/IDA)
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