The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kelch-type beta propeller
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Kelch-like family member 17

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
5 Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP4 (/ISS) Q6TDP4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q8K430 (/IPI) Q8K430 (/IPI) Q8K430 (/IPI)
POZ domain binding GO:0031208
Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.
3 Q8K430 (/IPI) Q8K430 (/IPI) Q8K430 (/IPI)
POZ domain binding GO:0031208
Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
5 Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP4 (/ISS) Q6TDP4 (/ISS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 Q8K430 (/IEP) Q8K430 (/IEP) Q8K430 (/IEP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
5 Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP3 (/ISS) Q6TDP4 (/ISS) Q6TDP4 (/ISS)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 Q8K430 (/IDA) Q8K430 (/IDA) Q8K430 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 Q6TDP3 (/ISO) Q6TDP3 (/ISO) Q6TDP3 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q6TDP4 (/HDA) Q6TDP4 (/HDA)
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