The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TolB, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 33: teneurin-a isoform X3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 O61307 (/IPI) Q9VYN8 (/IPI) Q9VYN8 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Filamin binding GO:0031005
Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
1 O61307 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 O61307 (/IDA)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Postsynaptic membrane organization GO:0001941
A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Synaptic target recognition GO:0008039
The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Synaptic target recognition GO:0008039
The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Synaptic target attraction GO:0016200
The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Regulation of homotypic cell-cell adhesion GO:0034110
Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Positive regulation of heterotypic cell-cell adhesion GO:0034116
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Synaptic vesicle membrane organization GO:0048499
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Maintenance of presynaptic active zone structure GO:0048790
A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Synaptic growth at neuromuscular junction GO:0051124
The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Presynaptic membrane organization GO:0097090
A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
3 O61307 (/IMP) Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Central complex development GO:0048036
The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.
2 Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
1 O61307 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
1 O61307 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
1 O61307 (/IMP)
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
1 O61307 (/IMP)
Regulation of homotypic cell-cell adhesion GO:0034110
Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
1 O61307 (/IMP)
Compound eye photoreceptor development GO:0042051
The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
1 O61307 (/IMP)
R7 cell development GO:0045467
The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.
1 O61307 (/IMP)
Compound eye corneal lens development GO:0048058
The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.
1 O61307 (/IMP)
Postsynaptic spectrin-associated cytoskeleton organization GO:0099190
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.
1 O61307 (/IDA)
Postsynaptic spectrin-associated cytoskeleton organization GO:0099190
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.
1 O61307 (/IMP)
Maintenance of alignment of postsynaptic density and presynaptic active zone GO:0099559
The process by which alignment between postsynaptic density and presynaptic active zone is maintained.
1 O61307 (/IDA)
Maintenance of alignment of postsynaptic density and presynaptic active zone GO:0099559
The process by which alignment between postsynaptic density and presynaptic active zone is maintained.
1 O61307 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
3 O61307 (/ISS) Q9VYN8 (/ISS) Q9VYN8 (/ISS)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 O61307 (/IDA) Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 Q9VYN8 (/ISM) Q9VYN8 (/ISM)
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
2 Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Presynaptic active zone GO:0048786
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
2 Q9VYN8 (/IDA) Q9VYN8 (/IDA)
Cytoskeleton of presynaptic active zone GO:0048788
The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.
2 Q9VYN8 (/IMP) Q9VYN8 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O61307 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 O61307 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 O61307 (/IDA)
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