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CATH Superfamily 2.102.10.10

Rieske [2Fe-2S] iron-sulphur domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rieske [2Fe-2S] iron-sulphur domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 26: mRNA, clone: RTFL01-01-M20

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pheophorbide a oxygenase. [EC: 1.14.15.17]
Pheophorbide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+) + O(2) = red chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster.
  • This enzyme catalyzes a key reaction in chlorophyll degradation, which occurs during leaf senescence and fruit ripening in higher plants.
  • The enzyme from Arabidopsis contains a Rieske-type iron-sulfur cluster and requires reduced ferredoxin, which is generated either by NADPH through the pentose-phosphate pathway or by the action of photosystem I.
  • While still attached to this enzyme, the product is rapidly converted into primary fluorescent chlorophyll catabolite by the action of EC 1.3.7.12.
  • Pheophorbide b acts as an inhibitor.
  • In (18)O(2) labelling experiments, only the aldehyde oxygen is labelled, suggesting that the other oxygen atom may originate from H(2)O.
  • Formerly EC 1.14.12.20.
 1 Q9FYC2
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