The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Complement Module, domain 1
".
FunFam 52: Complement factor B
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Alternative-complement-pathway C3/C5 convertase.
[EC: 3.4.21.47]
Cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha- chain to yield C5a and C5b.
|
9 | A0A1U9X7H8 A0A1U9X7H8 P00751 P00751 P04186 P04186 Q3UEG8 Q3UEG8 Q864V9 |
|
Classical-complement-pathway C3/C5 convertase.
[EC: 3.4.21.43]
Selective cleavage of Arg-|-Ser bond in complement component C3 alpha- chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b.
|
8 | P06681 P06681 P21180 Q5JP69 Q5JP69 Q863A0 Q8SQ74 Q8SQ75 |
