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CATH Superfamily 2.10.70.10

Complement Module, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Complement Module, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 161: Membrane cofactor protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
 2 A0A024CBD6 (/IDA) O02839 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
 2 A0A024CBD6 (/IDA) O02839 (/IDA)
Negative regulation of complement activation, alternative pathway GO:0045957
Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
 2 A0A024CBD6 (/IDA) O02839 (/IDA)
Negative regulation of complement activation, classical pathway GO:0045959
Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
 2 A0A024CBD6 (/IDA) O02839 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 2 A0A024CBD6 (/IDA) O02839 (/IDA)