The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Tyrosine-protein kinase receptorTyrosine-protein kinase receptorReceptor protein-tyrosine kinaseSC:2Receptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor tyrosine-protein kinase erbB-3SC:3R-spondin 3R-spondin 4Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseTyrosine-protein kinase receptorproprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 6Furin-like protease 2proprotein convertase subtilisin/kexin type 6proprotein convertase subtilisin/kexin type 5 isoform X2Furin, paired basic amino acid cleaving enzymeReceptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Tyrosine-protein kinase receptorFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Furin 2, isoform AProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Extracellular matrix protein FRAS1Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5bProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 4Proprotein convertase subtilisin/kexin type 5bProprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5proprotein convertase subtilisin/kexin type 6 isoform X1Proprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Furin-like protease 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Fraser extracellular matrix complex subunit 1Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproproteinExtracellular matrix protein FRAS1Furin 2, isoform DProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseFraser extracellular matrix complex subunit 1Erb-b2 receptor tyrosine kinase 3bGal/GalNAc lectin Igl2, putativeCXXC-rich proteinCXXC-rich, putativeHigh cysteine membrane protein TMK-likeFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5High cysteine membrane protein TMK-likeReceptor protein-tyrosine kinaseFurin-like protease 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aUncharacterized proteinProprotein convertase subtilisin/kexin type 6R-spondin-3High cysteine membrane protein TMK-likeInsulin-like receptorFurin 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 6Furin-like protease 2Receptor protein-tyrosine kinaseTyrosine-protein kinase receptorReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseFraser extracellular matrix complex subunit 1R-spondin 2Tyrosine-protein kinase receptorReceptor protein-tyrosine kinaseTyrosine-protein kinase receptorProprotein convertase subtilisin/kexin type 5aUncharacterized proteinFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5High cysteine membrane protein TMK-likeFurin2, putativeFurin-like protease 2Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin typePutative furin-like protease 2Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseErb-b2 receptor tyrosine kinase 3aFibronectin domain-containing proteinFurin-like protease 2R-spondin 1Endoprotease bli-4Tyrosine-protein kinase receptorProprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinTyrosine-protein kinase receptorreceptor tyrosine-protein kinase erbB-4-likeProprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5aFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Putative furin-like protease 2Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5R-spondin-3Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseUncharacterized proteinHigh cysteine membrane protein Group 5Uncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Uncharacterized proteinCXC-rich proteinProprotein convertase subtilisin/kexin type 5aReceptor protein-tyrosine kinaseUncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinTyrosine-protein kinase receptorUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 4Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Extracellular matrix protein FRAS1AGAP002915-PAUncharacterized proteinUncharacterized proteinUncharacterized proteinReceptor protein-tyrosine kinaseUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aUncharacterized proteinPredicted proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5Erb-b2 receptor tyrosine kinase 3aUncharacterized proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5Predicted proteinReceptor protein-tyrosine kinaseUncharacterized proteinProprotein convertase subtilisin/kexin type 5aUncharacterized proteinPredicted proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinErb-b2 receptor tyrosine kinase 3aProprotein convertase subtilisin/kexin type 5Extracellular matrix protein FRAS1Uncharacterized proteinFurin2, putativeProprotein convertase subtilisin/kexin type 4, furin, putativePredicted proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aPredicted protein
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FunFam 177: Proprotein convertase subtilisin/kexin type 5

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

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