The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cysteine Rich Protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: lipoma-preferred partner isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 B7ZV88 (/IPI) F1QSX8 (/IPI) H9XVP5 (/IPI) Q15654 (/IPI) Q5U0W6 (/IPI) Q7ZU85 (/IPI) Q8BFW7 (/IPI) Q8I0G8 (/IPI) Q8T0F5 (/IPI) Q93052 (/IPI)
(5 more)
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
3 Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
3 Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS)
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
2 Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
2 Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q15654 (/HDA)
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
1 Q15654 (/IDA)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
1 Q15654 (/IPI)
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
1 Q15654 (/NAS)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
5 H9XVP5 (/ISS) Q5U0W6 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Terminal branching, open tracheal system GO:0007430
Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Chitin-based cuticle sclerotization GO:0007593
The process of hardening of a chitin-based cuticle.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Liquid clearance, open tracheal system GO:0035002
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of imaginal disc growth GO:0045572
Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of eclosion GO:0045805
Any process that activates or increases the frequency, rate or extent of eclosion.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Imaginal disc-derived wing expansion GO:0048526
The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
5 H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
3 Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS)
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
3 B7ZV88 (/IGI) F1QSX8 (/IGI) Q7ZU85 (/IGI)
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
3 B7ZV88 (/IMP) F1QSX8 (/IMP) Q7ZU85 (/IMP)
Dorsal convergence GO:0060030
The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
3 B7ZV88 (/IMP) F1QSX8 (/IMP) Q7ZU85 (/IMP)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
3 Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
2 Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 Q15654 (/IMP)
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
1 Q9N675 (/IGI)
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
1 Q9N675 (/IMP)
Positive regulation of organ growth GO:0046622
Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
1 Q9N675 (/IMP)
Focal adhesion assembly GO:0048041
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
1 Q15654 (/NAS)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1 Q15654 (/IDA)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
8 H9XVP5 (/ISS) Q3SX26 (/ISS) Q5U0W6 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS)
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
5 H9XVP5 (/IDA) Q5U0W6 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 A0A087WZF1 (/IDA) Q15654 (/IDA) Q93052 (/IDA) Q93052 (/IDA) Q93052 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
5 H9XVP5 (/ISS) Q5U0W6 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
5 A0A087WZF1 (/IDA) Q15654 (/IDA) Q93052 (/IDA) Q93052 (/IDA) Q93052 (/IDA)
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
5 H9XVP5 (/IDA) Q5U0W6 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
4 Q15654 (/HDA) Q93052 (/HDA) Q93052 (/HDA) Q93052 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q8BFW7 (/ISO) Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
3 Q8BFW7 (/ISO) Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q15654 (/IDA)