A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.

Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.

The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.

An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.

A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.

Any process that activates or increases the activity of a GTPase.

The directed movement of a protein to a specific location.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.

Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.

Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.

Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.

Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.

Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.

The binding of a cell to the extracellular matrix via adhesion molecules.

Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.

A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.

Any process that activates or increases the activity of a GTPase.

The directed movement of a protein to a specific location.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.

The attachment of one cell to another cell via adhesion molecules.

The attachment of one cell to another cell via adhesion molecules.

Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.

Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.

Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.

A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.

Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.

A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.

Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.

Cytoplasm situated near, or occurring around, the nucleus.

A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.

Cytoplasm situated near, or occurring around, the nucleus.