The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cysteine Rich Protein
".
FunFam 27: lipoma-preferred partner isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
19 |
A5H447 (/IPI)
B7ZV88 (/IPI)
F1QSX8 (/IPI)
H9XVP5 (/IPI)
Q04584 (/IPI)
Q15654 (/IPI)
Q15942 (/IPI)
Q5U0W6 (/IPI)
Q62523 (/IPI)
Q7ZU85 (/IPI)
(9 more) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
3 | Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
3 | Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q15654 (/HDA) Q15942 (/HDA) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
2 | Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
2 | Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
1 | Q15654 (/IDA) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | A5H447 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | Q0VA45 (/ISS) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
1 | Q15654 (/IPI) |
|
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
|
1 | Q15654 (/NAS) |
|
Alpha-actinin binding GO:0051393
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
|
1 | Q04584 (/IPI) |
There are 33 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
5 | H9XVP5 (/ISS) Q5U0W6 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS) |
|
Terminal branching, open tracheal system GO:0007430
Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Chitin-based cuticle sclerotization GO:0007593
The process of hardening of a chitin-based cuticle.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Liquid clearance, open tracheal system GO:0035002
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Positive regulation of imaginal disc growth GO:0045572
Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Positive regulation of eclosion GO:0045805
Any process that activates or increases the frequency, rate or extent of eclosion.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Imaginal disc-derived wing expansion GO:0048526
The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
|
5 | H9XVP5 (/IMP) Q5U0W6 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
3 | Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS) |
|
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
3 | B7ZV88 (/IGI) F1QSX8 (/IGI) Q7ZU85 (/IGI) |
|
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
3 | B7ZV88 (/IMP) F1QSX8 (/IMP) Q7ZU85 (/IMP) |
|
Dorsal convergence GO:0060030
The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
|
3 | B7ZV88 (/IMP) F1QSX8 (/IMP) Q7ZU85 (/IMP) |
|
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
|
3 | Q3SX26 (/ISS) Q9Z1Y4 (/ISS) Q9Z1Y4 (/ISS) |
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q15942 (/IMP) Q62523 (/IMP) |
|
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q15942 (/IMP) Q62523 (/IMP) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
2 | Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
|
2 | Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | A5H447 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q0VA45 (/ISS) |
|
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | Q15942 (/IC) |
|
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | Q62523 (/IMP) |
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q62523 (/ISO) |
|
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q62523 (/ISO) |
|
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
1 | Q15942 (/TAS) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | Q15654 (/IMP) |
|
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
|
1 | Q9N675 (/IGI) |
|
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
|
1 | Q9N675 (/IMP) |
|
Stress fiber assembly GO:0043149
The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.
|
1 | Q15942 (/IMP) |
|
Stress fiber assembly GO:0043149
The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.
|
1 | Q62523 (/ISO) |
|
Positive regulation of organ growth GO:0046622
Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q9N675 (/IMP) |
|
Focal adhesion assembly GO:0048041
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
|
1 | Q15654 (/NAS) |
|
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
|
1 | D4A7U1 (/IEP) |
|
Cellular response to interferon-gamma GO:0071346
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.
|
1 | Q62523 (/IDA) |
|
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
|
1 | Q15654 (/IDA) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
11 |
A5H447 (/ISS)
G3USS0 (/ISS)
H9XVP5 (/ISS)
Q0VA45 (/ISS)
Q3SX26 (/ISS)
Q5U0W6 (/ISS)
Q8I0G8 (/ISS)
Q8T0F5 (/ISS)
Q9N675 (/ISS)
Q9Z1Y4 (/ISS)
(1 more) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
8 | A0A087WZF1 (/IDA) H0Y2Y8 (/IDA) Q04584 (/IDA) Q15654 (/IDA) Q15942 (/IDA) Q93052 (/IDA) Q93052 (/IDA) Q93052 (/IDA) |
|
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
|
7 | H9XVP5 (/IDA) Q04584 (/IDA) Q15942 (/IDA) Q5U0W6 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | A0A087WZF1 (/IDA) H0Y2Y8 (/IDA) Q15654 (/IDA) Q15942 (/IDA) Q93052 (/IDA) Q93052 (/IDA) Q93052 (/IDA) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
5 | H9XVP5 (/ISS) Q5U0W6 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
5 | Q15654 (/HDA) Q15942 (/HDA) Q93052 (/HDA) Q93052 (/HDA) Q93052 (/HDA) |
|
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
|
5 | H9XVP5 (/IDA) Q5U0W6 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q62523 (/ISO) Q8BFW7 (/ISO) Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
4 | Q62523 (/ISO) Q8BFW7 (/ISO) Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
|
3 | A5H447 (/ISS) G3USS0 (/ISS) Q0VA45 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9Z1Y4 (/ISO) Q9Z1Y4 (/ISO) |
|
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
|
1 | Q62523 (/ISO) |
|
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
1 | Q04584 (/IDA) |
|
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
1 | G3USS0 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q15942 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q62523 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q04584 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | G3USS0 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q15654 (/IDA) |
|
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
1 | Q15942 (/IDA) |
|
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
1 | Q62523 (/ISO) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q62523 (/IDA) |