The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cysteine Rich Protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 123: Rho GTPase-activating protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
6 P39083 (/IDA) P39083 (/IDA) P39083 (/IDA) Q06407 (/IDA) Q06407 (/IDA) Q06407 (/IDA)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
6 P39083 (/IGI) P39083 (/IGI) P39083 (/IGI) Q06407 (/IGI) Q06407 (/IGI) Q06407 (/IGI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P39083 (/IPI) P39083 (/IPI) P39083 (/IPI) Q06407 (/IPI) Q06407 (/IPI) Q06407 (/IPI)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
3 Q06407 (/ISA) Q06407 (/ISA) Q06407 (/ISA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Septin ring organization GO:0031106
Control of the formation, spatial distribution, and breakdown of the septin ring.
6 P39083 (/IGI) P39083 (/IGI) P39083 (/IGI) Q06407 (/IGI) Q06407 (/IGI) Q06407 (/IGI)
Pheromone-dependent signal transduction involved in conjugation with cellular fusion GO:0000750
A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
3 P39083 (/IGI) P39083 (/IGI) P39083 (/IGI)
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
3 P39083 (/IPI) P39083 (/IPI) P39083 (/IPI)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
3 P39083 (/IMP) P39083 (/IMP) P39083 (/IMP)
Budding cell apical bud growth GO:0007118
Growth at the tip of a bud, in a cell that reproduces by budding.
3 P39083 (/IPI) P39083 (/IPI) P39083 (/IPI)
Budding cell isotropic bud growth GO:0007119
Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.
3 P39083 (/IPI) P39083 (/IPI) P39083 (/IPI)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
3 Q06407 (/IMP) Q06407 (/IMP) Q06407 (/IMP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
3 P39083 (/IMP) P39083 (/IMP) P39083 (/IMP)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 Q06407 (/IDA) Q06407 (/IDA) Q06407 (/IDA)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 Q06407 (/IGI) Q06407 (/IGI) Q06407 (/IGI)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 Q06407 (/IMP) Q06407 (/IMP) Q06407 (/IMP)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 Q06407 (/IPI) Q06407 (/IPI) Q06407 (/IPI)
Positive regulation of pseudohyphal growth GO:2000222
Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.
3 P39083 (/IPI) P39083 (/IPI) P39083 (/IPI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular bud neck split septin rings GO:0032177
Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.
6 P39083 (/IDA) P39083 (/IDA) P39083 (/IDA) Q06407 (/IDA) Q06407 (/IDA) Q06407 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P39083 (/HDA) P39083 (/HDA) P39083 (/HDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
3 P39083 (/HDA) P39083 (/HDA) P39083 (/HDA)
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