The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Umud Fragment, subunit A
".
FunFam 5: Mitochondrial inner membrane protease subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
11 |
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
(1 more) |
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
|
9 | P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) P46972 (/IDA) |
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
|
9 | P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) |
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
1 | Q9UST2 (/ISS) |
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
1 | Q8BPT6 (/IGI) |
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
1 | Q8BPT6 (/IMP) |
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
1 | Q8BPT6 (/ISA) |
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | Q9UST2 (/ISM) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein processing involved in protein targeting to mitochondrion GO:0006627
The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
|
12 |
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
(2 more) |
Protein processing involved in protein targeting to mitochondrion GO:0006627
The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
|
9 | P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) P46972 (/IMP) |
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | Q8BPT6 (/IMP) |
Protein processing involved in protein targeting to mitochondrion GO:0006627
The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
|
1 | Q8BPT6 (/IGI) |
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | Q8BPT6 (/IMP) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q8BPT6 (/IMP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q8BPT6 (/IMP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q8BPT6 (/IMP) |
Blood circulation GO:0008015
The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.
|
1 | Q8BPT6 (/IMP) |
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q8BPT6 (/ISA) |
Respiratory electron transport chain GO:0022904
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
|
1 | Q8BPT6 (/IMP) |
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
|
1 | Q8BPT6 (/IMP) |
Mitochondrial respiratory chain complex assembly GO:0033108
The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.
|
1 | Q8BPT6 (/IMP) |
Cerebellum vasculature development GO:0061300
The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.
|
1 | Q8BPT6 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial inner membrane peptidase complex GO:0042720
Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
|
12 |
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
Q96T52 (/ISS)
(2 more) |
Mitochondrial inner membrane peptidase complex GO:0042720
Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
|
9 | P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) P46972 (/IPI) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q8BPT6 (/HDA) Q9UST2 (/HDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q8BPT6 (/ISA) |
Mitochondrial inner membrane peptidase complex GO:0042720
Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
|
1 | Q8BPT6 (/IGI) |