The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Mitochondrial 2-oxoglutarate/malate carrier protei...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dicarboxylic acid transmembrane transporter activity GO:0005310
Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
17 Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS)
(7 more)
Oxoglutarate:malate antiporter activity GO:0015367
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
17 Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA)
(7 more)
Dicarboxylic acid transmembrane transporter activity GO:0005310
Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Tricarboxylic acid transmembrane transporter activity GO:0015142
Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dicarboxylic acid transport GO:0006835
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
17 Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS)
(7 more)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
17 Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS)
(7 more)
Alpha-ketoglutarate transport GO:0015742
The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
17 Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS) Q8IB73 (/ISS)
(7 more)
Malate transport GO:0015743
The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
17 Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA)
(7 more)
Dicarboxylic acid transport GO:0006835
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Tricarboxylic acid transmembrane transport GO:0035674
The process in which a tricarboxylic acid is transported across a membrane.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
17 Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA) Q8IB73 (/IDA)
(7 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q9C5M0 (/IDA) Q9C5M0 (/IDA)
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